A widespread expression of c-fos was induced following an intraperitoneal injection of LPS and attenuated by vagotomy

被引：0
|
作者：
WANG Xi
机构：
来源：
ActaPharmacologicaSinica | 1999年 / 05期
关键词：
A widespread expression of c-fos was induced following an intraperitoneal injection of LPS and attenuated by vagotomy;
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暂无
中图分类号：
R363 [病理生理学];
学科分类号：
100104 ;
摘要：
It has been proposed that some of CNS responses to peripheral immune challenge are activated by a neural route especially via afferent fibers in the vagal nerve.In the present study, the expression of early-immediate gene c-fos in rat brain following an intraperitoneal injection of lipopolysaccharides ( LPS, 20 μg·kg-1) was observed and the effect of subdiaphragmatic vagotomy to the Fos expression as well as the existence of type Ⅰ of IL-1 receptor (IL-lRI) in nodose ganglion were examined by
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页码：91 / 91
页数：1
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