Research Progress on the Mechanism of Yuxingcao(Herba Houttuyniae) Against Diabetic Kidney Disease: A Review

Objective: To review the possible mechanism and clinical application of the main components of Yuxingcao(Herba Houttuyniae) in the treatment of diabetic kidney disease, and provide a certain theoretical basis for the prevention and treatment of diabetic nephropathy with Yuxingcao(Herba Houttuyniae). Methods: This study viewed on etiology and pathogenesis, main components and pharmacology, and mechanismd of Yuxingcao(Herba Houttuyniae); Researched on clinical study on prevention and treatment of Diabetic kidney disease. Results: The mechanism of Yuxingcao(Herba Houttuyniae) was reducing urinary protein, regulating lipid metabolism, regulating the expression of fibrosis-related factors and improving expression of inflammatory chemokines. It had the effects of clearing away heat and detoxifying, eliminating carbuncle and discharging pus, diuretic and relieving stranguria. Conclusion: The literatures studied have proved that Yuxingcao(Herba Houttuyniae) has antibacterial, antiviral, antioxidant, anti-infammatory, diuretic, antitumor and other effects. It is one of the common used herbal medicines for diabetic kidney disease.