Supercritical Antisolvent Precipitation of Microparticles of Quercetin

被引：0
|
作者：
刘学武
李志义
韩冰
苑塔亮
机构：
[1] China
[2] R&D Institute of Fluid and Powder Engineering Dalian University of Technology
[3] Dalian 116012
来源：
Chinese Journal of Chemical Engineering | 2005年 / 01期
关键词：
supercritical antisolvent process; microparticles; quercetin;
D O I：
暂无
中图分类号：
+ [];
学科分类号：
摘要：
Supercritical antisolvent (SAS) process is a recently developed technology to produce micro- and nano particles. This paper presents a continuous apparatus to conduct experiment of SAS process. With the apparatus, the effects of pressure, temperature and flow ratio of CO2 to the solution on the shape and size of particles are studied for the quercetin-ethanol-CO2 system. Spherical quercetin microparticles with diameters ranging form 1 μm to 6μm can be obtained while ethanol is used as organic solvent. The most effective fact on the shape and size of particles is pressure, the next is temperature and the last is the flow ratio of CO2 to solution.
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页码：134 / 136
页数：3
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