表皮干细胞增殖分化的分子调控机制

[1] Hyperproliferationand defects in epithelial polarity upon conditional ablation ofα-catenin in skin. Vasioukhin V,Bauer C,Degenstein L,et al. Cell . 2001

[2] Beta-catenin controlshair follicle morphogenesis and stem cell differentiation in theskin. Huelsken J,Vogel R,Erdmann B,et al. Cell . 2001

[3] Downregulation of14-3-3σ?prevents clonal evolution and leads to immortalizationof primary human keratinocytes. Dellambra E,Golisano O,Bondanza S,et al. The Journal of Cell Biology . 2000

[4] p63 identifies kerati-nocyte stem cells. Pellegrini G,Dellambra E,Golisano O,et al. Proceedings of the National Academy of Sciences of the United States of America . 2001

[5] Conditional ablation ofβ1 integrin in skin:severe defects in epidermal proliferation,basement membrane formation,and hair follicle invagination. Raghavan S,Bauer C,Mundschau G,et al. JCell Biol . 2000

[6] Stimulation of human epi-dermal differentiation by delta-notch sigalling at the boundariesof stem cell clusters. Lowell S,Jones P,Le Roux I,et al. Current Biology . 2000

[7] Shc regulates epidermalgrowth factor-induced activation of the JNK signaling pathway. Hashimoto A,Kurosaki M,Gotoh N. Journal of Biological Chemistry . 1999

[8] p63 is essential for regenera-tive proliferation in lumb,craniofacial and epithelial development. Yang A,Schweitzer R,Sun D,et al. Nature . 1999

[9] Notch signaling:cellgate control andsignal integration in development. Artavanis-Tsakonas S,Rand MD,Lake RJ. Science . 1999

[10] Beta-catenin singalling modulates proliferativepotential of human epidermal keratinocytes in dependently of in-tercellular adhesion. Zhu AJ,Watt FM. Development . 1999

[1] Hyperproliferationand defects in epithelial polarity upon conditional ablation ofα-catenin in skin. Vasioukhin V,Bauer C,Degenstein L,et al. Cell . 2001

[2] Beta-catenin controlshair follicle morphogenesis and stem cell differentiation in theskin. Huelsken J,Vogel R,Erdmann B,et al. Cell . 2001

[3] Downregulation of14-3-3σ?prevents clonal evolution and leads to immortalizationof primary human keratinocytes. Dellambra E,Golisano O,Bondanza S,et al. The Journal of Cell Biology . 2000

[4] p63 identifies kerati-nocyte stem cells. Pellegrini G,Dellambra E,Golisano O,et al. Proceedings of the National Academy of Sciences of the United States of America . 2001

[5] Conditional ablation ofβ1 integrin in skin:severe defects in epidermal proliferation,basement membrane formation,and hair follicle invagination. Raghavan S,Bauer C,Mundschau G,et al. JCell Biol . 2000

[6] Stimulation of human epi-dermal differentiation by delta-notch sigalling at the boundariesof stem cell clusters. Lowell S,Jones P,Le Roux I,et al. Current Biology . 2000

[7] Shc regulates epidermalgrowth factor-induced activation of the JNK signaling pathway. Hashimoto A,Kurosaki M,Gotoh N. Journal of Biological Chemistry . 1999

[8] p63 is essential for regenera-tive proliferation in lumb,craniofacial and epithelial development. Yang A,Schweitzer R,Sun D,et al. Nature . 1999

[9] Notch signaling:cellgate control andsignal integration in development. Artavanis-Tsakonas S,Rand MD,Lake RJ. Science . 1999

[10] Beta-catenin singalling modulates proliferativepotential of human epidermal keratinocytes in dependently of in-tercellular adhesion. Zhu AJ,Watt FM. Development . 1999