China’s food security mainly depends on the core areas of food production.Under the dual constraints of resource scarcity and environmental degradation,improving the grain production efficiency of the main grain-producing areas has become the fundamental way to strengthen the grain production capacity and improve the national food security capability,and to improve the efficiency of grain production in major grain-producing areas requires empirical support.This paper used the Super SBM model and the Malmquist index to measure the grain production efficiency of the main grain-producing areas from 2001 to 2020 from both static and dynamic perspectives,and compared the differences in grain production efficiency among different soil types and different provinces (autonomous regions) in the main grain-producing areas.The results showed that from 2001 to 2020,the grain production in the main grain-producing areas was in a relatively ineffective state,and the differences in grain production efficiency among different soil types and different provinces (autonomous regions) in the main grain-producing areas were obvious.The order of grain production efficiency in different soil types was black soil region>red-yellow soil region>paddy soil region>fluvo-aquic soil region,and the order of grain production efficiency of the provinces (autonomous regions) in the main grain-producing areas was Jilin>Heilongjiang>Inner Mongolia>Jiangxi>Hunan>Sichuan>Hubei>Jiangsu>Liaoning>Henan>Anhui>Shandong>Hebei.From 2001 to 2020,the total factor productivity of grain in the main grain-producing areas increased,but due to the trade-off between the technological progress and the growth of technical efficiency,the increase in the total factor productivity of grain in the main grain-producing areas was small,and the growth mainly came from the increase of input factors in this period.The total factor productivity of grain in Hebei,Heilongjiang,Liaoning,Jilin,Inner Mongolia,Shandong,Jiangsu,Henan and Anhui increased,but the increase was small,while the total factor productivity of grain in Jiangxi,Sichuan,Hunan and Hubei provinces declined.