Interferon γ in patients with HIV/AIDS and suspicion or latent tuberculosis infection

被引：0
|
作者：
Guadalupe Garcia-Elorriaga [1 ]
Mayte Martinez-Velazquez [2 ]
Veronica Gaona-Flores [2 ]
Guillermo del Rey-Pineda [3 ]
Cesar Gonzalez-Bonilla [1 ]
机构：
[1] Unidad de Investigacion en Inmunologia e Infectologia,Centro Medico Nacional La Raza(CMNR),Instituto Mexicano del Seguro Social(IMSS) Mexico City,Mexico
[2] Hospital de Infectologia,CMNR,IMSS,Mexico City,Mexico
[3] Banco Central de Sangre,CMNR.Hospital Infantil de Mexico,Federico Gomez.Dpto.de Infectologia
来源：
Asian Pacific Journal of Tropical Medicine | 2013年 / 02期
关键词：
AIDS; HIV; IGRA; Interferonγ; Latent tuberculosis infection;
D O I：
暂无
中图分类号：
R512.91 [获得性免疫缺陷综合征（AIDS艾滋病）];
学科分类号：
100401 ;
摘要：
Objective:To assess the usefulness of IGRA test(QuantiFERON?-Cell mediated immune) compared with the tuberculin skin test.Methods:A cross-sectional study was carried out in Mexico,25 infected patients with HIV-AIDS and the suspicion or with latent tuberculous infection (LTBI) who were>18 years of age and without treatment for tuberculosis(TB),were enrolled in the study.Results:Median cluster of differentiation(CD4) count was 364 cells/μL and median HIV viral load was 50 copies/mL.Overall,20 patients(80%) had at least one positive diagnostic test for LTBI:four(16%) had a positive tuberculin skin test and 19(76%),a positive QuantiFERON?-tuberculosis.Conclusions:No agreement is found between the two diagnostic tests:k = -0.004,95%confidence interval(-0.2219,0.2210).Additional longitudinal studies among HIV-infected populations with high prevalence of TB are needed to further assess the usefulness of IGRAs in this patient population.
引用
收藏
页码：157 / 160
页数：4
相关论文
共 50 条
  • [1] Interferon γ in patients with HIV/AIDS and suspicion or latent tuberculosis infection
    Garcia-Elorriaga, Guadalupe
    Martinez-Velazquez, Mayte
    Gaona-Flores, Veronica
    del Rey-Pineda, Guillermo
    Gonzalez-Bonilla, Cesar
    ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2013, 6 (02) : 135 - 138
  • [2] Active tuberculosis and Mycobacterium tuberculosis latent infection in patients with HIV/AIDS
    Gutierrez, E. B.
    Gomes, V.
    Picone, C. M.
    Suga, H.
    Atomiya, A. N.
    HIV MEDICINE, 2009, 10 (09) : 564 - 572
  • [3] Latent Tuberculosis and HIV Infection
    Bares, Sara H.
    Swindells, Susan
    CURRENT INFECTIOUS DISEASE REPORTS, 2020, 22 (07)
  • [4] Latent Tuberculosis and HIV Infection
    Sara H. Bares
    Susan Swindells
    Current Infectious Disease Reports, 2020, 22
  • [5] Latent tuberculosis in patients with recently diagnosed HIV infection
    Soto, L.
    Guevara, R. N.
    Landaeta, M. E.
    HIV MEDICINE, 2023, 24 : 328 - 328
  • [6] Changing Concepts of "Latent Tuberculosis Infection" in Patients Living with HIV Infection
    Lawn, Stephen D.
    Wood, Robin
    Wilkinson, Robert J.
    CLINICAL & DEVELOPMENTAL IMMUNOLOGY, 2011,
  • [7] Transmission of Mycobacterium tuberculosis from tuberculosis patients with HIV infection or AIDS
    Cauthen, GM
    Dooley, SW
    Onorato, IM
    Ihle, WW
    Burr, JM
    Bigler, WJ
    Witte, J
    Castro, KG
    AMERICAN JOURNAL OF EPIDEMIOLOGY, 1996, 144 (01) : 69 - 77
  • [8] Interferon-γ and Immunoglobulins in Latent Tuberculosis Infection
    Topic, Renata Zrinski
    Dodig, Slavica
    Zoricic-Letoja, Ivka
    ARCHIVES OF MEDICAL RESEARCH, 2009, 40 (02) : 103 - 108
  • [9] Practices and attitudes towards tuberculosis and latent tuberculosis infection screening in people living with HIV/AIDS among HIV physicians in Japan
    Lisa Kawatsu
    Noriyo Kaneko
    Mayumi Imahashi
    Keisuke Kamada
    Kazuhiro Uchimura
    AIDS Research and Therapy, 19
  • [10] Practices and attitudes towards tuberculosis and latent tuberculosis infection screening in people living with HIV/AIDS among HIV physicians in Japan
    Kawatsu, Lisa
    Kaneko, Noriyo
    Imahashi, Mayumi
    Kamada, Keisuke
    Uchimura, Kazuhiro
    AIDS RESEARCH AND THERAPY, 2022, 19 (01)
12345