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Effects of minimal lipopolysaccharide-instilled lungs on ventilator-induced lung injury in rats
被引:0
|作者:
LI Ke-zhong WANG Qiu-jun SUN Tao YAO Shang-long Department of Anesthesiology
机构:
来源:
基金:
中国国家自然科学基金;
关键词:
mechanical ventilation;
lung injury;
lipopolysaccharide;
D O I:
暂无
中图分类号:
R563 [肺疾病];
学科分类号:
1002 ;
100201 ;
摘要:
Mechanical ventilation(MV)may aggravate lunginjury induced by a variety of injuries,includingintratracheal hydrochloric acid instillation,intratracheallipopolysaccharide(LPS)instillation with or withoutconcurrent saline lavage,intravenous LPS,orintravenous oleic acid.However,the mechanism for thisdetrimental effect of MV is unclear.The purpose of thepresent study was to determine the effect of MV on lunginjury induced by minimal LPS-instillation and on theLPS receptor CDin the lung.
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页码:1451 / 1453
页数:3
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