Influence of Tacticity on the Self-Assembly of Poly(ethylene glycol)-b-poly(lactic acid) Block Copolymers

被引：0
|
作者：
Rijpkema, Sjoerd J. [1 ]
Toebes, B. Jelle [1 ]
van Vlaenderen, Jules [1 ]
van Haren, Liban [1 ]
Wilson, Daniela A. [1 ]
机构：
[1] Radboud Univ Nijmegen, Inst Mol & Mat, Heyendaalseweg 135, NL-6525 AJ Nijmegen, Netherlands
来源：
ACS MACRO LETTERS | 2025年 / 14卷 / 01期
关键词：
MOLECULAR-WEIGHT; MORPHOLOGIES; CHIRALITY; SOLVENT;
D O I：
10.1021/acsmacrolett.4c00758
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Lactide, possessing two stereocenters and thus three distinct configurations (DD, DL, and LL), serves as a captivating building block for polymers and self-assembly. Notably, polylactide (PLA) exhibits stereocomplexation, displaying heightened interactions between different configurations compared with interactions within the same configuration. This characteristic renders PLA an intriguing subject for investigating self-assembly behavior. In this study, 22 PEG-b-PLA polymers were synthesized and self-assembled, with analysis conducted through NMR and cryo-TEM techniques. A range of morphologies, including vesicles, diamond-shaped lamellae, and branched networks, were achieved by manipulating the tacticities. Enhanced comprehension of self-assembly interactions holds promise for advancing molecular recognition, self-replication, and asymmetric catalysis.
引用
收藏
页码：101 / 106
页数：6
相关论文
共 50 条
  • [1] Poly(ε-caprolactone)-b-poly(ethylene glycol)-b-poly (ε-caprolactone) triblock copolymers:: Synthesis and self-assembly in aqueous solutions
    Zhang, Yaqiong
    Guo, Shengrong
    Lu, Chengfei
    Liu, Li
    Li, Zonghai
    Gu, Jianren
    JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2007, 45 (04) : 605 - 613
  • [2] Poly (ethylene oxide) -b-Poly (ε-caprolactone) amphiphilic block copolymers: Synthesis and Self-assembly
    Kang, Kexin
    Liu, Minying
    Zhao, Qingxiang
    Fu, Peng
    Wang, Xiaobing
    MATERIALS AND DESIGN, PTS 1-3, 2011, 284-286 : 1877 - 1885
  • [3] Cooperation of Amphiphilicity and Crystallization for Regulating the Self-Assembly of Poly(ethylene glycol)-block-poly(lactic acid) Copolymers
    Wang, Zhen
    Cao, Yuanyuan
    Song, Jiaqi
    Xie, Zhigang
    Wang, Yapei
    LANGMUIR, 2016, 32 (37) : 9633 - 9639
  • [4] Self-assembly of poly(ethylene oxide)-b-poly(ε-caprolactone) copolymers in aqueous solution
    Vangeyte, P
    Leyh, B
    Heinrich, M
    Grandjean, J
    Bourgaux, C
    Jérôme, R
    LANGMUIR, 2004, 20 (20) : 8442 - 8451
  • [5] Self-assembly in a mixture of two poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) copolymers in water
    Zhou, DL
    Alexandridis, P
    Khan, A
    JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1996, 183 (02) : 339 - 350
  • [6] Concentration controlled multilevel self-assembly of 3-armed poly(ethylene glycol)-b-poly(ε-caprolactone) block copolymers investigated by AFM
    Guo, Shengrong
    Zhang, Yaqiong
    JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 2008, 46 (13) : 1412 - 1418
  • [7] Poly(lactic acid)-poly(ethylene oxide) Block Copolymers: New Directions in Self-Assembly and Biomedical Applications
    Saffer, E. M.
    Tew, G. N.
    Bhatia, S. R.
    CURRENT MEDICINAL CHEMISTRY, 2011, 18 (36) : 5676 - 5686
  • [8] Tacticity-induced changes in the micellization and degradation of poly(lactic acid)-block-poly(ethylene glycol) copolymers
    Shaver, Michael P.
    Agatemor, Christian
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [9] Self-assembly of poly(ethylene glycol)-based block copolymers for biomedical applications
    Otsuka, H
    Nagasaki, Y
    Kataoka, K
    CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, 2001, 6 (01) : 3 - 10
  • [10] Two-dimensional self-assembly of poly(ethylene oxide)-b-poly(ε-caprolactone) copolymers
    Joncheray, Thomas J.
    Denoncourt, Kristina M.
    Mathieu, Claire
    Meier, Michael A. R.
    Schubert, Ulrich S.
    Duran, Randolph S.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
12345