Tackling Infectious Diseases in the Caribbean and South America: Epidemiological Insights, Antibiotic Resistance, Associated Infectious Diseases in Immunological Disorders, Global Infection Response, and Experimental Anti-Idiotypic Vaccine Candidates Against Microorganisms of Public Health Importance

被引:0
|
作者
Justiz-Vaillant, Angel [1 ]
Soodeen, Sachin [1 ]
Gopaul, Darren [2 ]
Arozarena-Fundora, Rodolfo [3 ,4 ]
Thompson, Reinand [1 ]
Unakal, Chandrashekhar [1 ]
Akpaka, Patrick E. [1 ,3 ]
机构
[1] Univ West Indies, Dept Para Clin Sci, St Augustine Campus, St Augustine 330912, Trinidad Tobago
[2] Morehouse Sch Med, Dept Surg, Atlanta, GA 30310 USA
[3] North Cent Reg Hlth Author, Eric Williams Med Sci Complex, Champs Fleurs 330912, Trinidad Tobago
[4] Univ West Indies, Fac Med Sci, Dept Clin & Surg Sci, St Augustine 330912, Trinidad Tobago
关键词
HIV; nosocomial infections; antibiotic resistance; salmonella; blood-transfusion safety; immunology; West Indies; mycobacterium tuberculosis; Gram-negative bacteria; IgM antibodies; anti-idiotypic vaccines; STAPHYLOCOCCUS-AUREUS; MOLECULAR EPIDEMIOLOGY; MICROBIOME; PREVALENCE; ANTIBODIES; ENVELOPE; SKIN;
D O I
10.3390/microorganisms13020282
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
This paper explores various aspects of microbiology and immunology, with a particular focus on the epidemiology and molecular characterisation of infectious diseases in the Caribbean and South America. Key areas of investigation include tuberculosis (TB), experimental vaccines, and bloodborne pathogens. A retrospective study conducted in Jamaica highlights the significance of early HIV screening, timely diagnosis, and inte-grated care. The paper also examines the challenges posed by nosocomial infections, particularly those caused by antibiotic-resistant Gram-negative bacteria and methicillin-resistant Staphylococcus aureus (MRSA), emphasising the critical importance of infection control measures. Additionally, it explores the regional microbiome, the global response to infectious diseases, and immune responses in patients with immunodeficiency disorders such as severe combined immunodeficiency (SCID) and chronic granulomatous disease (CGD), underscoring their heightened susceptibility to a wide range of infections.
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页数:37
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