The deep shale gas resources of the Sichuan Basin are abundant and constitute an important component of China's natural gas production. Complicated by fault zones and other geostructures, the in situ stress state of the deep shale gas reservoirs in the Luzhou block remains poorly understood. This study integrated multiple datasets, including acoustic logging, diagnostic fracture injection testing (DFIT), imaging logging, and laboratory stress measurements, for calibration and constraint. A high-precision geomechanical model of the Luzhou block was constructed using the finite element method. This model characterizes the geomechanical properties of the reservoir and explores its applications in optimizing shale gas horizontal well placement, drilling processes, and fracture design. The study findings indicate that the Longmaxi Formation reservoir demonstrates abnormally high pore pressure, with gradients ranging from 16.7 to 21.7 kPa/m. The predominant stress regime is strike-slip, with an overburden stress gradient of 25.5 kPa/m and a minimum horizontal principal stress gradient ranging from 18.8 to 24.5 kPa/m. Based on a three-dimensional geomechanical model, a quantitative delineation of areas conducive to density reduction and pressure control drilling was conducted, and field experiments were implemented in well Y65-X. Utilizing an optimized drilling fluid density of 1.85 g/cm3, the deviated horizontal section was completed in a single trip, resulting in a 67% reduction in the drilling cycle compared to adjacent wells. Similarly, the Y2-X well demonstrated a test daily output of 506,900 cubic meters following an optimization of segmentation clustering and fracturing parameters. Studies indicate that 3D geomechanical modeling, informed by multi-source data constraints, can markedly enhance model precision, and such geomechanical models and their results can effectively augment drilling operational efficiency, elevate single-well production, and are advantageous for development.