Using Simulation to Optimize the Design of Adaptive Clinical Trials

被引：0
|
作者：
Robinson, Cal H. [1 ,2 ,3 ]
Parekh, Rulan S. [1 ,2 ,3 ,4 ]
Cuthbertson, Brian H. [5 ,6 ,7 ]
Fan, Eddy [5 ]
Ouyang, Yongdong [3 ,8 ]
Heath, Anna [3 ,8 ,9 ]
机构：
[1] Hosp Sick Children, Div Nephrol, Toronto, ON, Canada
[2] Univ Toronto, Dept Paediat, Toronto, ON, Canada
[3] Hosp Sick Children, Res Inst, Child Hlth Evaluat Sci, Toronto, ON, Canada
[4] Womens Coll Hosp, Dept Med, Toronto, ON, Canada
[5] Univ Toronto, Interdept Div Crit Care Med, Toronto, ON, Canada
[6] Sunnybrook Hlth Sci Ctr, Res Inst, Toronto, ON, Canada
[7] Sunnybrook Hlth Sci Ctr, Dept Crit Care Med, Toronto, ON, Canada
[8] Univ Toronto, Dalla Lana Sch Publ Hlth, Div Biostat, Toronto, ON, Canada
[9] UCL, Dept Stat Sci, London, England
来源：
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | 2024年
基金：
加拿大健康研究院;
关键词：
children; clinical epidemiology; clinical trial; nephrotic syndrome; pediatric nephrology; biostatistics;
D O I：
10.1681/ASN.0000000565
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [1] The Bayesian Design of Adaptive Clinical Trials
    Giovagnoli, Alessandra
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, 18 (02) : 1 - 15
  • [2] Adaptive design methods in clinical trials
    Wade, Angela
    JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 2007, 170 : 1179 - 1180
  • [3] Confirmatory clinical trials with an adaptive design
    Koch, Armin
    BIOMETRICAL JOURNAL, 2006, 48 (04) : 574 - 585
  • [4] Adaptive design methods in clinical trials
    Wade, Angela
    JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 2008, 171 : 314 - 314
  • [5] Development of a model-based clinical trial simulation platform to optimize the design of clinical trials for Duchenne muscular dystrophy
    Lingineni, Karthik
    Aggarwal, Varun
    Morales, Juan Francisco
    Conrado, Daniela J.
    Corey, Diane
    Vong, Camille
    Burton, Jackson
    Larkindale, Jane
    Romero, Klaus
    Schmidt, Stephan
    Kim, Sarah
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2022, 11 (03): : 318 - 332
  • [6] Design and implementation of pragmatic clinical trials using the electronic medical record and an adaptive design
    Simon, Kelly Claire
    Tideman, Samuel
    Hillman, Laura
    Lai, Rebekah
    Jathar, Raman
    Ji, Yuan
    Bergman-Bock, Stuart
    Castle, James
    Franada, Tiffani
    Freedom, Thomas
    Marcus, Revital
    Mark, Angela
    Meyers, Steven
    Rubin, Susan
    Semenov, Irene
    Yucus, Chad
    Pham, Anna
    Garduno, Lisette
    Szela, Monika
    Frigerio, Roberta
    Maraganore, Demetrius M.
    JAMIA OPEN, 2018, 1 (01) : 99 - 106
  • [7] Computational design of clinical trials using a combination of simulation and the genetic algorithm
    Tsuchiwata, Shinichi
    Tsuji, Yasuhiro
    CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2023, 12 (04): : 522 - 531
  • [8] Systematic Review of Adaptive Design Clinical Trials
    Bothwell, Laura
    Khan, Nazleen
    Kesselheim, Aaron
    PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2015, 24 : 583 - 584
  • [9] Ethical Considerations in Adaptive Design Clinical Trials
    Laage, Thomas
    Loewy, John W.
    Menon, Sandeep
    Miller, Eva R.
    Pulkstenis, Erik
    Kan-Dobrosky, Natalia
    Coffey, Christopher
    THERAPEUTIC INNOVATION & REGULATORY SCIENCE, 2017, 51 (02) : 190 - 199
  • [10] Ethical Considerations in Adaptive Design Clinical Trials
    Thomas Laage
    John W. Loewy
    Sandeep Menon
    Eva R. Miller
    Erik Pulkstenis
    Natalia Kan-Dobrosky
    Christopher Coffey
    Therapeutic Innovation & Regulatory Science, 2017, 51 : 190 - 199
12345