Visual Performance and Satisfaction of Extended Depth of Focus Contact Lenses in Presbyopic Subjects

Background/Objectives: The objective was to assess visual performance and the overall satisfaction of extended-depth-of-focus (EDOF) contact lenses (CLs) in a presbyopic population. Methods: We prospectively investigated visual acuity at all distances (0.3, 0.4, 0.5, 0.7, 1, and 5 m), higher-order aberrations (HOAs), contrast sensitivity function, and overall satisfaction score, before and during EDOF CL wear in 42 eyes of 21 presbyopic subjects (1 man and 20 women). Results: Binocular visual acuity at 0.3, 0.5, 0.7, 1, 2, 3, and 5 m when wearing EDOF CLs was 0.01 +/- 0.14, -0.08 +/- 0.02, -0.08 +/- 0.02, -0.08 +/- 0.00, -0.08 +/- 0.00, -0.08 +/- 0.02, and -0.07 +/- 0.02, respectively. We found a significant improvement at near to intermediate distances (0.3, and 0.5 m), but no significant change at intermediate to far distances (0.7, 1, 2, 3, and 5 m) between before and during CL wear. The area under the log contrast sensitivity function was not significantly changed under photopic nor mesopic conditions (p = 0.099, and p = 0.689). Ocular third-order aberrations, fourth-order aberrations, or total HOAs for a 4 mm pupil significantly increased. The overall satisfaction score significantly improved by wearing EDOF CLs. Conclusions: EDOF CLs significantly improved visual acuity at near to intermediate distances, while maintaining far vision, and the effect of contrast sensitivity was minimal, suggesting the viability of presbyopic correction in such candidates.