Resist or degrade? In vitro gastrointestinal digestion and health impact of legume-derived bioactive peptides

被引：0

作者：

Feng, Weiwei ^{[1
]}

Liu, Chunhong ^{[1
]}

Chen, Xueqiang ^{[2
]}

Ye, Bin ^{[1
]}

Olatunji, Opeyemi Joshua ^{[3
]}

Ashaolu, Tolulope Joshua ^{[4
,5
]}

机构：

[1] Second Peoples Hosp, Wuhu City, Anhui, Peoples R China

[2] Zhejiang Chinese Med Univ, Tradit Chinese Med Hosp, Hangzhou, Zhejiang, Peoples R China

[3] Mohammed VI Polytech Univ, African Genome Ctr, Ben Guerir 43150, Morocco

[4] Duy Tan Univ, Inst Global Hlth Innovat, Da Nang 550000, Vietnam

[5] Duy Tan Univ, Fac Med, Da Nang 550000, Vietnam

来源：

FOOD BIOSCIENCE | 2025年 / 63卷

关键词：

Legume protein; Legume-derived peptides; Gastrointestinal digestion; In vitro digestion; Bioactive peptides; HYDROLYZED SOYBEAN HYDROLYSATE; HEAT-INDUCED AGGREGATION; ANTIOXIDANT ACTIVITY; DIETARY PEPTIDES; CANCER CELLS; INTESTINAL PERMEABILITY; ANTIMICROBIAL ACTIVITY; FUNCTIONAL-PROPERTIES; PROTEIN HYDROLYSATE; OXIDATIVE STRESS;

D O I：

10.1016/j.fbio.2024.105684

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Legumes are a group of environmentally sustainable major crops with rich nutritional profiles such as vitamins, fibers, minerals, antioxidants, and proteins, making them a great alternative to animal-derived proteins. The significance and importance of legumes cannot be overemphasized since they contain multifarious types of proteins, and are consumed globally. Legume-derived peptides (LDPs) are known for their biological activities and potential health benefits including gastrointestinal (GI) health maintenance. Some of these peptides resist digestion while others do not, especially at the gastric and duodenal/intestinal phases. This study reviews the GI digestion (GID), extraction, and isolation of legume proteins, and the separation/purification of LDPs. Studies on LDPs' in vitro GID are comparable based on resistance or digestibility, and their impacts on human GI health. Although the GI health benefits of LDPs have been established, contrasting data on their in vitro GID necessitate further robust studies on LDPs using in vitro, in vivo, and clinical strategies.

引用

页数：10