Connection between oral health and chronic diseases

被引:0
|
作者
Fu, Di [1 ]
Shu, Xingyue [1 ]
Zhou, Ge [1 ]
Ji, Mengzhen [1 ]
Liao, Ga [1 ,2 ]
Zou, Ling [3 ]
机构
[1] Sichuan Univ, Natl Clin Res Ctr Oral Dis, Natl Ctr Stomatol, State Key Lab Oral Dis, Chengdu, Sichuan, Peoples R China
[2] Sichuan Univ, West China Hosp Stomatol, Dept Informat Management, Dept Stomatol Informat, Chengdu, Sichuan, Peoples R China
[3] Sichuan Univ, West China Hosp Stomatol, Natl Ctr Stomatol, Natl Clin Res Ctr Oral Dis,State Key Lab Oral Dis,, Chengdu 610041, Sichuan, Peoples R China
来源
MEDCOMM | 2025年 / 6卷 / 01期
基金
中国国家自然科学基金;
关键词
cardiovascular diseases; chronic diseases; chronic respiratory diseases; diabetes; oral health; rheumatoid arthritis; TYPE-2; DIABETES-MELLITUS; GINGIVAL CREVICULAR FLUID; NONSURGICAL PERIODONTAL TREATMENT; GLYCATION END-PRODUCTS; RHEUMATOID-ARTHRITIS PATIENTS; NECROSIS-FACTOR-ALPHA; INTENSIVE-CARE-UNIT; APICAL PERIODONTITIS; MATRIX METALLOPROTEINASES; DENTAL-CARIES;
D O I
10.1002/mco2.70052
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Chronic diseases have emerged as a paramount global health burden, accounting for 74% of global mortality and causing substantial economic losses. The oral cavity serves as a critical indicator of overall health and is inextricably linked to chronic disorders. Neglecting oral health can exacerbate localized pathologies and accelerate the progression of chronic conditions, whereas effective management has the potential to reduce their incidence and mortality. Nevertheless, limited resources and lack of awareness often impede timely dental intervention, delaying optimal therapeutic measures. This review provides a comprehensive analysis of the impact of prevalent chronic diseases-such as diabetes mellitus, rheumatoid arthritis, cardiovascular disorders, and chronic respiratory diseases-on oral health, along with an exploration of how changes in oral health affect these chronic conditions through both deterioration and intervention mechanisms. Additionally, novel insights into the underlying pathophysiological mechanisms governing these relationships are presented. By synthesizing these advancements, this review aims to illuminate the complex interrelationship between oral health and chronic diseases while emphasizing the urgent need for greater collaboration between dental practitioners and general healthcare providers to improve overall health outcomes.
引用
收藏
页数:27
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