Regulatory Components for Bacterial Cell-Free Systems Engineering

被引：0

作者：

Lee, Pao-Wan ^{[1
]}

Maerkl, Sebastian J. ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Inst Bioengn, Sch Engn, CH-1015 Lausanne, Switzerland

来源：

ACS SYNTHETIC BIOLOGY | 2024年

基金：

瑞士国家科学基金会;

关键词：

Synthetic biology; Gene regulatory network; Cell-free Systems; Gene circuits; FREE TRANSLATION; GENE-EXPRESSION; ZINC FINGERS; RNA; CONSTRUCTION; PRINCIPLES; NETWORKS; ROBUST; SWITCH; MODEL;

D O I：

10.1021/acssynbio.4c00574

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Cell-free systems are advancing synthetic biology through fast prototyping and modularity. Complex regulatory networks can now be implemented in cell-free systems enabling various applications, such as diagnostic tool development, gene circuit prototyping, and metabolic engineering. As functional complexity increases, the need for regulatory components also grows. This review provides a comprehensive overview of native as well as engineered regulatory components and their use in bacterial cell-free systems.

引用

页数：15

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