Getting to the Heart of the Matter: Exploring the Intersection of Cardiovascular Disease, Sex and Race and How Exercise, and Gut Microbiota Influence these Relationships

被引：0

作者：

Guers, John J. ^{[1
]}

Heffernan, Kevin S. ^{[2
]}

Campbell, Sara C. ^{[3
,4
]}

机构：

[1] Rider Univ, Dept Hlth Sci & Nursing, Lawrenceville, NJ 08648 USA

[2] Columbia Univ, Teachers Coll, Dept Biobehav Sci, New York, NY 10027 USA

[3] State Univ New Jersey, Dept Kinesiol & Hlth, New Brunswick, NJ 08901 USA

[4] Rutgers State Univ, Nutr Microbiome & Hlth, Ctr Human Nutr Exercise & Metab, Rutgers Ctr Lipid Res, New Brunswick, NJ 08901 USA

来源：

REVIEWS IN CARDIOVASCULAR MEDICINE | 2025年 / 26卷 / 02期

关键词：

cardiovascular disease; ethnicity; microbiome; heart; intestine; physical activity; LEFT-VENTRICULAR MASS; ENDOTHELIUM-DEPENDENT VASODILATION; INDUCED-MYOCARDIAL-ISCHEMIA; IMPROVES VASCULAR FUNCTION; CORONARY-ARTERY-DISEASE; NITRIC-OXIDE PRODUCTION; AFRICAN-AMERICAN WOMEN; TERM ESTROGEN THERAPY; PULSE-WAVE VELOCITY; OXIDATIVE STRESS;

D O I：

10.31083/RCM26430

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiovascular disease (CVD) is the leading cause of death worldwide, with physical inactivity being a known contributor to the global rates of CVD incidence. CVD incidence, however, is not uniform with recognized sex differences as well and racial and ethnic differences. Furthermore, gut microbiota have been associated with CVD, sex, and race/ethnicity. Researchers have begun to examine the interplay of these complicated yet interrelated topics. This review will present evidence that CVD (risk and development), and gut microbiota are distinct between the sexes and racial/ethnic groups, which appear to be influenced by acculturation, discrimination, stress, and lifestyle factors like exercise. Furthermore, this review will address the beneficial impacts of exercise on the cardiovascular system and will provide recommendations for future research in the field.

引用

页数：28