Conversion of bla KPC-2 to bla KPC-33 leads to worldwide emergence of ceftazidime-avibactam resistance in Klebsiella pneumoniae

被引：1
|
作者：
Lai, Yi-Chyi [1 ]
Lin, Luo-Wei [2 ]
Cheng, Yi-Chen [3 ]
Lee, Yu-Lin [2 ,4 ,5 ]
机构：
[1] Chung Shan Med Univ, Sch Med, Dept Microbiol & Immunol, Taichung, Taiwan
[2] Chung Shan Med Univ Hosp, Dept Internal Med, 110,Sec 1Jianguo N Rd, Taichung 402, Taiwan
[3] Chung Shan Med Univ Hosp, Dept Lab Med, Taichung, Taiwan
[4] Chung Shan Med Univ, Sch Med, Taichung, Taiwan
[5] Natl Chung Hsing Univ, Inst Genom & Bioinformat, Taichung, Taiwan
来源：
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2024年 / 64卷 / 05期
关键词：
D O I：
10.1016/j.ijantimicag.2024.107342
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Emergence of ceftazidime-avibactam resistance through in-vivo bla KPC-2 to bla KPC-33 conversion during treatment of ST11 Klebsiella pneumoniae associated infections
    Lai, Yi-Chyi
    Lin, Luo-Wei
    Lee, Yu-Lin
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2024, 64 (02)
  • [2] Klebsiella pneumoniae carbapenemase (KPC) producer resistant to ceftazidime-avibactam due to a deletion in the bla KPC3 gene
    Antinori, E.
    Unali, I
    Bertoncelli, A.
    Mazzariol, A.
    CLINICAL MICROBIOLOGY AND INFECTION, 2020, 26 (07) : 946.e1 - 946.e3
  • [3] Aztreonam and ceftazidime-avibactam overlay in extensively drug-resistant bla NDM-5 , bla KPC-2 and bla OXA-181 carbapenemase-producing Klebsiella pneumoniae
    Koos, Georgia
    Rizzo, Sophia
    Siarakas, Steven
    Merlino, John
    PATHOLOGY, 2025, 57 (01) : 107 - 109
  • [4] Emergence of KPC-134, a KPC-2 variant associated with ceftazidime-avibactam resistance in a ST11 Klebsiella pneumoniae clinical strain
    Huang, Xiangning
    Shen, Siquan
    Chang, Fan
    Liu, Xin
    Yue, Jinxi
    Xie, Ning
    Yin, Lin
    Hu, Fupin
    Xiao, Daiwen
    MICROBIOLOGY SPECTRUM, 2023,
  • [5] Emergence of KPC-134, a KPC-2 variant associated with ceftazidime-avibactam resistance in a ST11 Klebsiella pneumoniae clinical strain
    Huang, Xiangning
    Shen, Siquan
    Chang, Fan
    Liu, Xin
    Yue, Jinxi
    Xie, Ning
    Yin, Lin
    Hu, Fupin
    Xiao, Daiwen
    MICROBIOLOGY SPECTRUM, 2023, 11 (05):
  • [6] Identification of bla KPC-90 in Klebsiella pneumoniae associated with ceftazidime-avibactam resistance and the translocation & truncation of resistant genes mediated by IS26
    Yang, Weiwei
    Xu, Heping
    Zhao, Yuanxun
    Chen, Wannan
    Ma, Xiaobo
    Hu, Fupin
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2025, 65 (01)
  • [7] KPC-Mediated Resistance to Ceftazidime-Avibactam and Collateral Effects in Klebsiella pneumoniae
    Findlay, Jacqueline
    Poirel, Laurent
    Juhas, Mario
    Nordmann, Patrice
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 65 (09)
  • [8] Avibactam/ceftazidimeEmergence of avibactam/ceftazidime resistance in KPC-2 producing Klebsiella pneumoniae infection: case report
    Reactions Weekly, 2019, 1768 (1) : 60 - 60
  • [9] Emergence of colistin resistance in Klebsiella pneumoniae ST15 disseminating bla KPC-2 in a novel genetic platform
    Alvarez, Veronica E.
    Masso, Mariana G.
    Gonzalez, Gabriela D'amico
    Gambino, Anahi S.
    Knecht, Camila A.
    Mc Cormick, Barbara Prack
    Leguina, Carolina
    Piekar, Maria
    Poklepovich, Tomas
    Campos, Josefina
    Arduino, Sonia
    Centron, Daniela
    Quiroga, Maria P.
    JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 2022, 29 : 537 - 539
  • [10] Ceftazidime-avibactam resistance in KPC-producing Klebsiella pneumoniae accompanied hypermucoviscosity acquisition
    Guo, Yingyi
    Wang, Jiong
    Yao, Likang
    Wang, Yijing
    Zhang, Yan
    Zhuo, Chuyue
    Yang, Xu
    Li, Feifeng
    Li, Jiahui
    Liu, Baomo
    He, Nanhao
    Chen, Jiakang
    Xiao, Shunian
    Lin, Zhiwei
    Zhuo, Chao
    BMC MICROBIOLOGY, 2024, 24 (01):
12345