ANTIMICROBIAL ACTIVITY A CHELIDONIUM SPECIES MAJUS L.

被引:0
|
作者
Topor, Gabi [1 ]
Stanescu, Cristina [1 ]
Buzia, Olimpia Dumitriu [1 ]
Forna, Doriana Agop [2 ]
Serban, Cristina [1 ]
机构
[1] Dunarea Jos Univ, Fac Med & Pharm, 35 Al I Cuza Str, Galati 800010, Romania
[2] Grigore T Popa Univ Med & Pharm, Fac Dent, Iasi, Romania
来源
关键词
simple ointment; base III; soft rosehip extract; gram positive; negative bacteria; Candida albicans; REHABILITATION; PARAMETERS;
D O I
10.6261/RJOR.2024.3.16.68
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The present paper has as main objective the determination of the antimicrobial and antifungal activity of some pharmaceutical forms obtained in the laboratory of pharmaceutical technology of the Faculty of Pharmacy of the University "Lower Danube of Galati". We used semi-solid pharmaceutical forms with different concentrations of soft extract of Chelidonium majus L, 50%, 25% and 10% in two ointment bases, simple ointment and base III I performed the antimicrobial activity for all four ointments, compared to extract 1: 3.75 in hydroalcoholic solution (ethyl alcohol / water 35/65 by mass) from aerial parts of Chelidonium majus and alcohol 70 degrees. hydroalcoholic solution was obtained by cold preparation from the aerial parts of the plant Chelidonium majus.We determined the antimicrobial activity by the diffusimetric method (Kirby-Bauer) and the dilution method. The 50% concentration ointment (UNG A) shows activity on some Gram-negative and Gram-positive bacteria and not on the fungus Candida albicans.
引用
收藏
页码:678 / 687
页数:10
相关论文
共 50 条
  • [1] Propagation of Chelidonium majus L. by somatic embryogenesis
    Vinterhalter, B
    Vinterhalter, D
    BIOLOGIA PLANTARUM, 2002, 45 (04) : 489 - 493
  • [2] SEASONAL VARIABILITY OF CHELIDONIUM MAJUS L. SECONDARY METABOLITES CONTENT AND ANTIOXIDANT ACTIVITY
    Jakovljevic, Z. Dragana
    Stankovic, S. Milan
    Topuzovic, D. Marina
    EXCLI JOURNAL, 2013, 12 : 260 - 268
  • [3] Phytochemical and pharmacological studies of Chelidonium majus L. (Papaveraceae)
    Varga, E.
    Tatar, T. K.
    Belak, A.
    Maraz, A.
    PLANTA MEDICA, 2015, 81 (16) : 1467 - 1467
  • [4] Chelidonium majus L. derivate Ukrain® inhibits metastasing
    Olga, Prokopchuk
    Wassil, Nowicky
    ACTA PHARMACOLOGICA SINICA, 2006, 27 : 71 - 71
  • [5] Stereospecific aminopeptidases in Chelidonium majus L. callus culture
    Benesova, M
    Blanarikova, S
    Kovacs, P
    Psenak, M
    CHEMICAL PAPERS, 1998, 52 : 592 - 592
  • [6] Isolation and Characterization of Bacterial Endophytes of Chelidonium majus L.
    Goryluk, Agata
    Rekosz-Burlaga, Hanna
    Blaszczyk, Mieczyslaw
    POLISH JOURNAL OF MICROBIOLOGY, 2009, 58 (04) : 355 - 361
  • [7] Sensitivity of Fusarium strains to Chelidonium majus L. extracts
    Matos, OC
    Baeta, J
    Silva, MJ
    Ricardo, CPP
    JOURNAL OF ETHNOPHARMACOLOGY, 1999, 66 (02) : 151 - 158
  • [8] Chemical analysis and antimicrobial activity of methanol extracts of celandine (Chelidonium majus L.) plants growing in nature and cultured in vitro
    Ciric, Ana
    Vinterhalter, Branka
    Savikin-Fodulovic, Katarina
    Sokovic, Marina
    Vinterhalter, D.
    ARCHIVES OF BIOLOGICAL SCIENCES, 2008, 60 (01) : 7P - 8P
  • [9] One new alkaloid from Chelidonium majus L.
    Zhang, Wen-Juan
    You, Chun-Xue
    Wang, Cheng-Fang
    Fan, Li
    Wang, Ying
    Su, Yang
    Deng, Zhi-Wei
    Du, Shu-Shan
    NATURAL PRODUCT RESEARCH, 2014, 28 (21) : 1873 - 1878
  • [10] A New Method for Alkaloid Extraction from Chelidonium majus L.
    Bugatti, C.
    Colombo, M. L.
    Tome, F.
    PHYTOCHEMICAL ANALYSIS, 1991, 2 (02) : 65 - 67