Safety, efficacy, and cost-effectiveness evaluation of systemic treatments for refractory colorectal cancer: a systematic review and modeling study

被引：0
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作者：
Mingye Zhao [1 ]
Yunlin Jiang [2 ]
Taihang Shao [3 ]
Wenxi Tang [4 ]
机构：
[1] China Pharmaceutical University,Department of Pharmacoeconomics, School of International Pharmaceutical Business
[2] China Pharmaceutical University,Center for Pharmacoeconomics and Outcomes Research
[3] Shanghai University of Traditional Chinese Medicine,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
[4] The Chinese University of Hong Kong,School of Public Health, Faculty of Medicine
[5] China Pharmaceutical University,Center for Pharmacoeconomics and Outcomes Research, Department of Public Affairs Management, School of International Pharmaceutical Business
来源：
Health Economics Review | / 15卷 / 1期
关键词：
Refractory colorectal cancer; Individual patient data meta-analysis; Cost-effectiveness; Efficacy; Safety;
D O I：
10.1186/s13561-025-00622-x
中图分类号：
学科分类号：
摘要：
Our pioneering meta-analysis introduces reconstructed IPD to derive robust survival metrics for refractory CRC, setting a new standard by accounting for event censoring. Consistent OS and PFS estimates from high-quality studies provide precise treatment insights and aid in designing future trial sample sizes.
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