LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers

被引：0

作者：

Hellmann, Margareta J. ^{[1
]}

Moerschbacher, Bruno M. ^{[1
]}

Cord-Landwehr, Stefan ^{[1
]}

机构：

[1] Univ Munster, Inst Biol & Biotechnol Plants, Schlosspl 8, D-48143 Munster, Germany

来源：

SOFTWAREX | 2025年 / 29卷

关键词：

enzymatic cleavage; linear copolymers; chitosan; web tool; glycoside hydrolase; DEACETYLATED CHITINS CHITOSANS; FIELD NMR-SPECTROSCOPY; PECTIN; ACETYLATION; OLIGOSACCHARIDES; SPECIFICITIES; DEGRADATION; OLIGOMERS; INSIGHT; LYASE;

D O I：

10.1016/j.softx.2025.102050

中图分类号：

TP31 [计算机软件];

学科分类号：

081202 ; 0835 ;

摘要：

The composition and enzymatic cleavage of binary linear copolymers (LCPs) composed of two different units, such as the glycans chitosan, homogalacturonan, alginate, or hyaluronan, are widely investigated by researchers from various disciplines including biomedicine, material sciences, and biotechnology. The LCP Simulator is a user-friendly free web tool available to anyone without registration at https://lcp-simulator.anvil.app. The objective is to provide support for LCP-researchers, including those lacking experience in in silico analyses, by offering a low-threshold possibility to simulate a) the analysis of distributions of the two units within LCPs, and b) the influence of LCP properties on the composition of products after cleavage with enzymes of defined subsite specificities.

引用

页数：6