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Optic Nerve Glioblastoma with Optic Chiasm Involvement: A Case Report and a Brief Literature Review
被引:0
|作者:
Brokans, Artis
[1
,2
]
Dolgopolova, Julija
[3
]
Saulitis, Agnis
[3
]
Spulle, Uldis
[4
]
Rancans, Kristaps
[3
]
Meiers, Dairis
[5
]
Hasnere, Sigita
[6
]
Balodis, Arturs
[1
,2
]
机构:
[1] Riga Stradins Univ, Dept Radiol, 16 Dzirciema St, LV-1007 Riga, Latvia
[2] Pauls Stradins Clin Univ Hosp, Inst Diagnost Radiol, 13 Pilsonu St, LV-1002 Riga, Latvia
[3] Pauls Stradins Clin Univ Hosp, Dept Neurosurg, 13 Pilsonu St, LV-1002 Riga, Latvia
[4] RSU Inst Stomatol, Dept Oral & Maxillofacial Surg, LV-1007 Riga, Latvia
[5] Pauls Stradins Clin Univ Hosp, Dept Ophthalmol, 13 Pilsonu St, LV-1002 Riga, Latvia
[6] Pauls Stradins Clin Univ Hosp, Dept Oncol, 13 Pilsonu St, LV-1002 Riga, Latvia
来源:
关键词:
optic nerve glioblastoma;
radiology;
neurosurgery;
ophthalmology;
ADJUVANT TEMOZOLOMIDE;
RADIOTHERAPY;
CONCOMITANT;
GLIOMA;
D O I:
10.3390/medicina60101687
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Background: optic nerve glioblastoma is an uncommon pathology. The optic chiasm, optic tract, or optic nerves are possible places from which the tumor can originate. Most of the neuroimaging findings are nonspecific. To confirm the diagnosis, a biopsy is required. A delay to the treatment plan for optic nerve glioblastoma results in poor patient survival rates. Case report: a 68-year-old woman with an uncomplicated medical history presented with exophthalmos, deteriorating eyesight, and partial loss of vision. Using radiological data together with postoperative histopathological and histochemical analysis, optic nerve glioblastoma, IDH-wildtype, with optic chiasm involvement was diagnosed. Conclusion: optic nerve glioblastoma is a rare and aggressive form of cancer that affects the optic nerve, leading to significant vision impairment and potentially life-threatening complications. Treatment options are restricted and difficult because of the location and nature of the condition; surgery, radiation therapy, and chemotherapy are frequently needed as part of a multidisciplinary approach.
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