Biodistribution of ARMMs as Non-Viral Vehicles for Delivery of Therapeutic Payloads by Subretinal Administration in Minipigs and Non-Human Primates

被引：0
|
作者：
Chinchore, Yashodhan [1 ]
Yang, Jinling [1 ]
Miller, Adam [1 ]
Moharil, Pearl [1 ]
Yu, Qin [1 ]
Nabhan, Joseph [1 ]
机构：
[1] Vesigen Therapeut, Cambridge, MA USA
来源：
MOLECULAR THERAPY | 2024年 / 32卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
663
引用
收藏
页码：337 / 337
页数：1
相关论文
共 50 条
  • [1] Biodistribution of ARMMs as Non-Viral Vehicles for Therapeutic Payloads by Sub-Retinal Administration in Minipigs and NHP
    Chinchore, Yashodhan
    Yang, Jinling
    Miller, Adam
    Semple, Carson
    Moharil, Pearl
    Bryant, Alysia
    Greenway, Steven
    Francoeur, Adam
    Gens, Leah
    Luther, Kristin
    Hao, Gary
    Yu, Qin
    Nabhan, Joseph
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2024, 65 (07)
  • [2] ARMMs as Non-Viral Vehicles for the Delivery of Therapeutic Payloads to Liver Sinusoidal Endothelial Cells
    von Kleeck, Ryan
    Liu, Shu-Lin
    Semple, Carson
    Sun, Lucy
    Moharil, Pearl
    Zhao, Wendy
    Badji, Jennifer
    Appiah, Emmanuel
    Le, Kevin
    Greenway, Steven
    Yu, Qin
    Nabhan, Joseph
    MOLECULAR THERAPY, 2024, 32 (04) : 590 - 590
  • [3] Engineering ARMMs with Modular T Cell-Specific Engagers for Non-Viral Delivery of Therapeutic Payloads
    Zhao, Wendy
    Sun, Lucy
    Wang, Qiyu
    Moharil, Pearl
    Thomas, Mike
    Piccinotti, Silvia
    Baghbantaraghdari, Zahra
    Chang, Chou-Wei
    Yu, Qin
    Nabhan, Joseph F.
    MOLECULAR THERAPY, 2024, 32 (04) : 594 - 594
  • [4] Non-Viral Gene Delivery of Human FVIII to Hemophilia A Mice and Non-Human Primates
    Stanton, Matthew G.
    Klatte, Deb
    Chiocco, Matt
    Hamm, Luke
    Nelson, Elizabeth
    Feinstein, Greg
    Gallagher, Nolan
    Su, Jie
    Milstead, Andrew
    Bush, Di
    Monds, Russell
    Parsonnet, Nicholas
    Penvose, Ashley
    LaGoy, Sarah
    Hansen, Erik
    Kittel, Jonathan
    Lymar, Anastasia
    Vu, Kati
    Joyce, Michelle Rodriguez
    Malakian, Karl
    Moffitt, Jeff
    MOLECULAR THERAPY, 2021, 29 (04) : 337 - 337
  • [5] ARMMs as a Versatile Non-Viral Delivery Platform for Therapeutic RNA Molecules
    Valkov, Nedyalka
    Gurwani, Bhavesh
    Chatzinakos, Chris
    Sun, Lucy
    Wang, Qiyu
    Luther, Kristin
    Francoeur, Adam
    Chinchore, Yashodhan
    Kim, Sophie
    Bryant, Alysia
    Gens, Leah
    Nabhan, Joseph F.
    MOLECULAR THERAPY, 2023, 31 (04) : 283 - 283
  • [6] ARMMs as Non-Viral Vehicles for the Delivery of Genome Editors to Treat Inherited Retinal Diseases
    Yang, Jinling
    Zhao, Wendy
    Chinchore, Yashodhan
    Baghbantaraghdari, Zahra
    Badji, Jennifer A.
    Wang, Qiyu
    Chang, Chou-Wei
    Miller, Adam
    Yu, Qin
    Nabhan, Joseph F.
    MOLECULAR THERAPY, 2024, 32 (04) : 335 - 336
  • [7] Engineering Directed Tropism in the Non-Viral ARMMs Delivery Platform
    Piccinotti, Silvia
    Thomas, Mike
    Zhao, Wendy
    Valkov, Nelly
    Schupp, Patrick
    Wang, Qiyu
    Sun, Lucy
    Liu, Shu-Lin
    Baghbantaraghdari, Zahra
    Chang, Chou-Wei
    Zhou, Hongru
    Yu, Qin
    Nabhan, Joseph
    MOLECULAR THERAPY, 2024, 32 (04) : 594 - 595
  • [8] rAAV8 biodistribution and shedding after subretinal injection in non-human primates
    Seitz, Immanuel Philipp
    Fischer, M. Dominik
    Michalakis, Stylianos
    Wilhelm, Barbara
    Kahle, Nadine
    Zrenner, Eberhart
    Ueffing, Marius
    Bartz-Schmidt, Karl Ulrich
    Biel, Martin
    Wissinger, Bernd
    Peters, Tobias
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (12)
  • [9] Non-viral generation of transgenic non-human primates via the piggyBac transposon system
    Nakaya, Masataka
    Iwatani, Chizuru
    Tsukiyama-Fujii, Setsuko
    Mieda, Ai
    Tarumoto, Shoko
    Tsujimura, Taro
    Yamamoto, Takuya
    Ichikawa, Takafumi
    Nakamura, Tomonori
    Terakado, Ichiro
    Kawamoto, Ikuo
    Nakagawa, Takahiro
    Itagaki, Iori
    Saitou, Mitinori
    Tsuchiya, Hideaki
    Tsukiyama, Tomoyuki
    NATURE COMMUNICATIONS, 2025, 16 (01)
  • [10] In vivo biodistribution of non-viral systems for oligoribonucleotides delivery
    Rimessi, P.
    Sabatelli, P.
    Gualandi, F.
    Spitali, P.
    Bovolenta, M.
    Martoni, E.
    Fabris, M.
    Nigro, V.
    Nusco, E.
    Calzolari, E.
    Ferlini, A.
    NEUROMUSCULAR DISORDERS, 2007, 17 (9-10) : 782 - 782
12345