Oxalis tuberosa fiber (OTF) was used to obtain a potentially functional and well accepted sensorially white bread. OTF showed a dietary fiber content of 88.51 %, which, once added to white bread formulations: 3 (WB3), 6 (WB6), and 10 % (WB10) (w/w), significantly (p <= 0.05) reduced the loaf volume. Breads with OTF showed yellow tones (degrees Hue = 76.40) with different chromaticity values and perceptible color change compared to control (bread without OTF). OTF significantly increased (p <= 0.05) the firmness and chewiness of breads, decreasing bread resilience. The estimated glycemic index was significantly lower (p <= 0.05) than the control (94.61) in the bread samples [40.62 (WB3)>35.54 (WB6)>27.23 (WB10)]. Finally, bread samples received a sensory evaluation of "like slightly", and a global acceptance index of 74.41, 70.32, and 72.80, for WB3, WB6, and WB10, respectively, which were similar to that of the control (75.85). Therefore, OTF used as an ingredient contributes to the production of hypoglycemic and sensory-accepted white bread with desired and attractive techno-functional properties, being considered a promising alternative to increase dietary fiber consumption promoting a healthier lifestyle through the control and prevention of metabolic diseases including metabolic syndrome and type 2 diabetes.