Synergistic Effects of Nintedanib With BCL-2 Inhibition to Drive Pro-fibrotic Fibroblast Apoptosis

被引：0
|
作者：
Cooley, J. [1 ]
Wilson, J. [2 ]
Javkhlan, N. [2 ]
Schwartz, D. A. [3 ]
Riches, D. W. [2 ]
Redente, E. F. [2 ]
机构：
[1] Natl Jewish Hlth, Pulm & Crit Care, Denver, CO USA
[2] Natl Jewish Hlth, Pediat, Denver, CO USA
[3] Univ Colorado, Dept Med, Aurora, CO USA
来源：
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2024年 / 209卷
关键词：
D O I：
暂无
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A3232
引用
收藏
页数：1
相关论文
共 50 条
  • [1] THE INHIBITION OF PRO-FIBROTIC RESPONSE IN CARDIAC FIBROBLASTS BY BASIC FIBROBLAST GROWTH FACTOR
    Kinoshita, T.
    Akasaka, Y.
    Ikeda, T.
    WOUND REPAIR AND REGENERATION, 2014, 22 (01) : A10 - A10
  • [2] Bcl-2 overexpression in hepatic stellate cell line CFSC-2G, induces a pro-fibrotic state
    Gonzalez-Puertos, Viridiana Y.
    Hernandez-Perez, Elizabeth
    Nuno-Lambarri, Natalia
    Ventura-Gallegos, Jose L.
    Lopez-Diazguerrero, Norma E.
    Robles-Diaz, Guillermo
    Gutierrez-Ruiz, Maria C.
    Konigsberg, Mina
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2010, 25 (07) : 1306 - 1314
  • [3] Matrix Stiffness And Fiber Organization Differentially Drive The Pro-Fibrotic Fibroblast Phenotype Through Myosin Ii
    Southern, B. D.
    Grove, L. M.
    Rahaman, S. O.
    Abraham, S.
    Niese, K.
    Scheraga, R. G.
    Olman, M. A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191
  • [4] The Novel Small Molecule BTB Inhibits Pro-Fibrotic Fibroblast Behavior though Inhibition of RhoA Activity
    Rackow, Ashley R.
    Nagel, David J.
    Zapas, Gregory
    Clough, Ryan S.
    Sime, Patricia J.
    Kottmann, R. Matthew
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (19)
  • [5] Small Molecule G[beta][gamma] Inhibition Attenuates Cardiac Fibroblast Inflammatory and Pro-Fibrotic Signaling
    Travers, Joshua G.
    Kamal, Fadia A.
    Burhans, Michael S.
    Blaxall, Burns C.
    CIRCULATION RESEARCH, 2014, 115
  • [6] Inhibition of Fas-induced apoptosis by Bcl-2
    Kawahara, A
    Kobayashi, T
    Nagata, S
    ONCOGENE, 1998, 17 (20) : 2549 - 2554
  • [7] INHIBITION OF CERAMIDE-INDUCED APOPTOSIS BY BCL-2
    MARTIN, SJ
    TAKAYAMA, S
    MCGAHON, AJ
    MIYASHITA, T
    CORBEIL, J
    KOLESNICK, RN
    REED, JC
    GREEN, DR
    CELL DEATH AND DIFFERENTIATION, 1995, 2 (04): : 253 - 257
  • [8] Inhibition of Fas-induced apoptosis by Bcl-2
    Atsuo Kawahara
    Toshiko Kobayashi
    Shigekazu Nagata
    Oncogene, 1998, 17 : 2549 - 2554
  • [9] Fibroblast Growth Factor 2 as an Antifibrotic: Antagonism of Myofibroblast Differentiation and Suppression of Pro-Fibrotic Gene Expression
    Dolivo, David M.
    Larson, Sara A.
    Dominko, Tanja
    CYTOKINE & GROWTH FACTOR REVIEWS, 2017, 38 : 49 - 58
  • [10] Synergistic Bcl-2 inhibition by ABT-737 and cyclosporine A
    Pietro E. Cippà
    Jivko Kamarashev
    Jin Chen
    Anna K. Kraus
    Stephan Segerer
    Laurence Feldmeyer
    Thomas Fehr
    Apoptosis, 2013, 18 : 315 - 323
12345