The sensitive and rapid detection of n-butanol gas is crucial for ensuring industrial safety, environmental protection, and biological health. In this study, we employed electrospinning to fabricate a series of CuBi2O4 nanofibers and nanotubes, followed by thorough characterization and analysis of their structural and functional features using XRD, FE-SEM, TEM, and XPS techniques. The gas-sensing performance demonstrates that CuBi2O4 nanotubes (CBO-500) exhibit an exceptionally rapid response to n-butanol, highlighting their potential for use in high-sensitivity n-butanol sensors. The sensor exhibited a response of 12.30-10 ppm n-butanol at 150 degrees C, with a rapid response time of 2 s and a recovery time of 41 s. Furthermore, the sensors based on CBO-500 nanotubes exhibited excellent selective. In addition, this study elucidates the underlying mechanisms responsible for the gas-sensing properties of CuBi2O4 nanotubes toward n-butanol.