For ecological safety and public health, it is essential to identify the causes of pollution in water sources and the effects of both natural and human activities. A class of secondary pollutants known as disinfection byproducts (DBPs) is produced when water is treated with disinfectant. Global problems include DBP formation, monitoring, and health effects in drinkable water. Because of the negative health effects of drinking chlorinated water and some DBPs, water manufacturers have made an attempt to balance pathogen elimination with DBP monitoring. The primary obstacles to managing DBPs are their low concentrations and the viability of their extensive use from a technical and economic perspective. Adsorption on activated carbons, ion exchange, membrane processes, and reducing precursors like NOMs are some of the techniques that may be used in controlling DBPs. The application of both new and conventional disinfection technologies in the removal of ARB and ARGs is also summarized in this review, with an emphasis on bacterial inactivation mechanisms like ozonation, chlorination, ultraviolet (UV), sunlight, sunlight-dissolved organic matter (DOM), and photocatalysis/photoelectrocatalysis (PEC).