[1] Jena Univ Hosp, Dept Anesthesiol & Intens Care Med, Jena, Germany
[2] Univ Leipzig, Inst Med Informat Stat & Epidemiol IMISE, Leipzig, Germany
[3] Univ Leipzig, Clin Trial Ctr Leipzig, Leipzig, Germany
[4] Radboud Univ Nijmegen Med Ctr, Dept Internal Med, Nijmegen, Netherlands
[5] Univ Bonn, Life & Med Sci Inst, Dept Immunol & Metab, Bonn, Germany
[6] Natl & Kapodistrian Univ Athens, Dept Internal Med 4, Med Sch, Athens, Greece