Common genetic variants contribute more to rare diseases than previously thought

被引：0

作者：

Breen, Gerome ^{[1
]}

机构：

[1] Kings Coll London, Social Genet & Dev Psychiat, Ctr Inst Psychiat Psychol, London SE5 8AF, England

来源：

NATURE | 2024年

关键词：

Genomics; DNA sequencing; Diseases;

D O I：

10.1038/d41586-024-03554-4

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In rare diseases, rare mutations have long been thought of as the only contributor. Genetic analyses of people with such conditions now suggest that the effects of common genetic variants can stack up and contribute to disease risk.

引用

页码：304 / 305

页数：2

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