Long-term outcomes in thoracic aortic surgery: 11 year single centre experience

被引:0
|
作者
Staniforth, Edward [1 ]
Ttofi, Iakovos [2 ]
Ttofi, Jasmina [2 ]
Perinparajah, Vanitha [2 ]
Vijjhalwar, Rohit [1 ]
Uberoi, Raman [3 ]
Sideso, Ediri [4 ]
Dubey, Shirish [5 ,6 ]
Krasopoulos, George [2 ,7 ]
机构
[1] Univ Oxford, Med Sch, Med Sci Div, Oxford, England
[2] Oxford Univ Hosp NHS Fdn Trust, John Radcliffe Hosp, Dept Cardiac Surg, Oxford, England
[3] Oxford Univ Hosp NHS Fdn Trust, John Radcliffe Hosp, Dept Radiol, Oxford, England
[4] Oxford Univ Hosp NHS Fdn Trust, John Radcliffe Hosp, Dept Vasc Surg, Oxford, England
[5] Oxford Univ Hosp, Dept Rheumatol, Oxford, England
[6] Univ Oxford, Nuffield Dept Musculoskeletal Sci, Windmill Rd, Oxford, England
[7] Oxford Univ Hosp NHS Fdn Trust, Oxford Heart Ctr, Dept Cardiac Surg, Headley Way, Oxford OX3 9DU, England
关键词
Cardiac surgery; Aorta; Aortic aneurysm; Type a aortic dissection; Follow-up;
D O I
10.1186/s13019-024-03153-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
ObjectivesThoracic aortic aneurysms and dissections provide a complex surgical cohort termed thoracic aortic surgery. Regular follow-up at specialist clinics with cross-sectional imaging is recommended. Identifying risk factors that lead to re-operations as well as the requirement for and appropriate length of follow-up remain points of debate.MethodsPatients undergoing thoracic aortic surgery performed at a single centre from January 2012 to December 2022 were retrospectively reviewed. The clinical information, operative details, histological reports, post-operative outcomes and follow up were collected from electronic patient records. Statistical analysis was performed using Microsoft Excel and R Studio.Results409 patients met the inclusion criteria for the study with a median follow-up of 3.8 years (IQR 1.6-7.6). The prevalence of all cause re-operations was 10.8% (n = 44). The median time to re-operation was 1.8 years. 68% of the reoperations occurred within the first 5 years. Multi and univariate logistic regression identified young age, arteritis and/or aortitis as the main risk factors associated with increased risk of re-operation. Connective tissue disease and systemic inflammatory diseases approached but didn't meet statistical significance. Bicuspid aortic valve pathology was associated with reduced risk of re-operation.ConclusionsPatients undergoing thoracic aortic surgery have a high rate of re-operation. The first 5 years represent a high-risk period and follow-up with cross-sectional imaging during that time by specialist aortic services is essential. Patient with aortitis remain at high risk and should be treated by appropriate by specialist aortic services with subspecialty interest and expertise on treating patients with aortitis.
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页数:9
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