STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma

被引：2

作者：

Lu, Dingheng ^{[1
]}

Li, Yuxiao ^{[2
]}

Niu, Xinyang ^{[1
]}

Sun, Jiazhu ^{[1
]}

Zhan, Weitao ^{[1
]}

Shi, Yuchen ^{[1
]}

Yu, Kai ^{[1
]}

Huang, Suyuelin ^{[1
]}

Liu, Xiaoyan ^{[2
]}

Xie, Liping ^{[1
]}

Ma, Xueyou ^{[1
,3
]}

Liu, Ben ^{[1
,3
]}

机构：

[1] Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, Hangzhou,310003, China

[2] Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, Hangzhou,310003, China

[3] Cancer Center, Zhejiang University, Zhejiang, Hangzhou,310003, China

来源：

Research | 2024年 / 7卷

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

Binding sites - Biomolecules - Coenzymes - Gene encoding - Light polarization - Metabolites - Mitochondria - Targeted drug delivery;

D O I：

10.34133/research.0539

中图分类号：

学科分类号：

摘要：

引用

共 23 条

[1] Vascular mimicry induced by m6A mediated IGFL2-AS1/AR axis contributes to pazopanib resistance in clear cell renal cell carcinoma
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Cell Death Discovery, 9
[2] Vascular mimicry induced by m6A mediated IGFL2-AS1/AR axis contributes to pazopanib resistance in clear cell renal cell carcinoma
Cheng, Bo
Xie, Mingyue
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Yu, Wenjing
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CELL DEATH DISCOVERY, 2023, 9 (01)
[3] Blocking the autocrine regulatory loop of Gankyrin/STAT3/CCL24/CCR3 impairs the progression and pazopanib resistance of clear cell renal cell carcinoma
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Cell Death & Disease, 11
[4] Blocking the autocrine regulatory loop of Gankyrin/STAT3/CCL24/CCR3 impairs the progression and pazopanib resistance of clear cell renal cell carcinoma
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CELL DEATH & DISEASE, 2020, 11 (02)
[5] PBX1 promotes the cell proliferation via JAK2/STAT3 signaling in clear cell renal carcinoma
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 500 (03) : 650 - 657
[6] MIER2/PGC1A elicits sunitinib resistance via lipid metabolism in renal cell carcinoma
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[7] TBC1D5 reverses the capability of HIF-2α in tumor progression and lipid metabolism in clear cell renal cell carcinoma by regulating the autophagy
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[8] IL1R2 promotes tumor progression via JAK2/STAT3 pathway in human clear cell renal cell carcinoma
Liu, Yingting
Xing, Zhaoyu
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Zhang, Dachuan
Zhou, You
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PATHOLOGY RESEARCH AND PRACTICE, 2022, 238
[9] IFITM3-mediated activation of TRAF6/MAPK/AP-1 pathways induces acquired TKI resistance in clear cell renal cell carcinoma
Jeong, Se Un
Park, Ja-Min
Yoon, Sun Young
Hwang, Hee Sang
Go, Heounjeong
Shin, Dong-Myung
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INVESTIGATIVE AND CLINICAL UROLOGY, 2024, 65 (01) : 84 - 93
[10] ERβ-Mediated Alteration of circATP2B1 and miR-204-3p Signaling Promotes Invasion of Clear Cell Renal Cell Carcinoma
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CANCER RESEARCH, 2018, 78 (10) : 2550 - 2563

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