Calcium greases were manufactured from olive-residue oil in a closed reactor by substituting olive-residue oil for animal tallow. The results of the performance tests applied to the obtained greases showed that their physicochemical and mechanical characteristics are comparable to those of calcium grease manufactured industrially by using animal tallow. The substitution of part of the animal tallow with olive-residue oil increased the thermal and mechanical stability of the grease. Olive-residue oil could constitute, alone or in combination with animal tallow, a raw material in the formulation of lubricating calcium grease.