CEPHALOSPORIN C ACYLASE, PART I. ISOLATION AND CULTIVATION OF CEPHALOSPORIN C ACYLASE-PRODUCING MICROORGANISM.

被引：0
|
作者：
Kawate, Shohei [1 ]
Fukuo, Tsuyoshi [1 ]
Kunito, Kazuya [1 ]
机构：
[1] Kansai Univ, Osaka, Jpn, Kansai Univ, Osaka, Jpn
来源：
Technology Reports of Kansai University | 1987年 / 29期
关键词：
BACTERIOLOGY; -; BIOTECHNOLOGY; Microbiology;
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摘要：
Paecilomyces sp. C-2106 that possesses cephalosporin C (CPC) acylase activity capable of deacylating CPC to produce 7-amino cephalosporanic acid (7-ACA) was isolated. The 7-ACA production was identified by the antibacterial activity and spectrum of the activated compound, thin layer chromatography (TLC), high performance liquid chromatography (HPLC), and inactivation with beta -lactamase.
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页码：77 / 94
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