This research aims to introduce and examine the innovative instructional design model with Mobile Technology for undergraduates of the School of Liberal Arts at Sukhothai Thammathirat Open University. Furthermore, it will evaluate the innovative instructional design model accordingly. The participants in the project comprised 30 undergraduates from the Information Science program, Thai Studies program, and English program who took the Science, Technology and Environment for Life course. They were selected through the cluster sampling technique. The research instruments comprised the innovative instructional design model, evaluation forms and the pre and post-achievement tests. Included as well was the questionnaire on undergraduates’ opinions towards the model. The data analysis used the mean, the standard deviation, and the t-test. In addition, the model contains distance learning lessons which have been developed by Mobile Technology, and have passed educational quality assurance measures. It has been categorized regarding content, educational technology, and assessment by experts in content, educational technology, and assessment. The innovative instructional design has also been rated as “most appropriate” by five experts in the areas of distance education, mobile technology, educational technology, assessment, and content. The undergraduates learning from the innovative instructional design model showed significant achievement at the.05 level and their satisfaction was rated at the “high satisfaction” level. © 2023,International Journal of Interactive Mobile Technologies. All Rights Reserved.