Conformational ensembles of non-peptide ω-conotoxin mimetics and Ca+2 ion binding to human voltage-gated N-type calcium channel Cav2.2

被引：0
|
作者：
Sameera [1 ]
Shah, Fawad Ali [2 ]
Rashid, Sajid [1 ]
机构：
[1] National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan
[2] Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan
来源：
Computational and Structural Biotechnology Journal | 2020年 / 18卷
关键词：
Peptides;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：2357 / 2372
相关论文
共 34 条
  • [1] Conformational ensembles of non-peptide ω-conotoxin mimetics and Ca+2 ion binding to human voltage-gated N-type calcium channel Cav2.2
    Sameera
    Shah, Fawad Ali
    Rashid, Sajid
    COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2020, 18 : 2357 - 2372
  • [2] Getting a handle on CaV2.2 (N-type) voltage-gated Ca2+ channels
    Striessnig, Joerg
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (51) : 12848 - 12850
  • [3] CaV2.2 (N-type) voltage-gated calcium channels are activated by SUMOylation pathways
    Silveirinha, Vasco C.
    Lin, Hong
    Tanifuji, Shota
    Mochida, Sumiko
    Cottrell, Graeme S.
    Cimarosti, Helena
    Stephens, Gary J.
    CELL CALCIUM, 2021, 93
  • [4] Formation of N-type (Cav2.2) voltage-gated calcium channel membrane microdomains: Lipid raft association and clustering
    Robinson, Philip
    Etheridge, Sarah
    Song, Lele
    Armenise, Paul
    Jones, Owen T.
    Fitzgerald, Elizabeth M.
    CELL CALCIUM, 2010, 48 (04) : 183 - 194
  • [5] CAV2.2 (N-TYPE) VOLTAGE-GATED CALCIUM CHANNELS ARE ACTIVATED BY SUMO-1 PROTEIN
    Silveirinha, V. C.
    Lin, H.
    Tanifuji, S.
    Mochida, S.
    Cottrell, G. S.
    Cimarosti, H.
    Stephens, G. J.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2017, 121 : 63 - 64
  • [6] A Selective Peptidomimetic Modulator Of Cav2.2 (N-Type) Voltage-Gated Calcium Channels For Chronic Pain
    Gomez, Kimberly
    Santiago, Ulises
    Calderon-Rivera, Aida
    Duran, Paz
    Loya-Lopez, Santiago
    Ran, Dongzhi
    Perez-Miller, Samantha
    Handoko, Handoko
    Arora, Paramjit S.
    Patek, Marcel
    King, Tamara D.
    Hu, Huijuan
    Camacho, Carlos J.
    Khanna, Rajesh
    JOURNAL OF PAIN, 2023, 24 (04): : 32 - 33
  • [7] Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
    Huynh, Thuan G.
    Cuny, Hartmut
    Slesinger, Paul A.
    Adams, David J.
    MOLECULAR PHARMACOLOGY, 2015, 87 (02) : 240 - 250
  • [8] Synthesis and Cav2.2 binding data for non-peptide mimetics of ω-conotoxin GVIA based on a 5-amino-anthranilamide core
    Duggan, Peter J.
    Faber, Jonathan M.
    Graham, Janease E.
    Lewis, Richard J.
    Lumsden, Natalie G.
    Tuck, Kellie L.
    AUSTRALIAN JOURNAL OF CHEMISTRY, 2008, 61 (01) : 11 - 15
  • [9] Modeling the binding of.-conotoxin and other toxins to the N-type voltage-gated calcium channel
    Sha, Serena
    Guillen-Tapia, Ashley
    Welch, Sophie
    Lavin, Emily Schmitt
    Sikora, Arthur
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 299 (03) : S550 - S551
  • [10] The Regulation of N-Type (cav2.2) Voltage-Gated Calcium Channels by Cavβ Subunit N- and C-terminal Variable Domains
    Song, Lele
    Roberts, Laura
    Fitzgerald, Elizabeth
    BIOPHYSICAL JOURNAL, 2010, 98 (03) : 694A - 694A
1234