A flexible wearable wireless fetal ECG monitoring system

被引：0
|
作者：
Yang H. [1 ]
Xia J. [1 ]
Chen B. [2 ]
Tang R. [2 ]
Chen Y. [2 ]
Ai J. [2 ]
Fu J. [2 ]
机构：
[1] Zhejiang Center for Medical Device Evaluation, Hangzhou
[2] Institute of Flexible Electronics Technolog of THU, Jiaxing
来源：
Zhongguo Kexue Jishu Kexue/Scientia Sinica Technologica | 2022年 / 52卷 / 12期
关键词：
fetal ECG; flexible fabrication; flexible wearable system; long-term and wireless monitoring; micro-nano machining;
D O I：
10.1360/SST-2021-0237
中图分类号：
学科分类号：
摘要：
Fetal heart rate monitoring can effectively reflect the health of a fetus and provide an important basis for diagnosing fetal diseases. Further, continuous and accurate fetal heart rate monitoring can guide prenatal and postnatal care. However, available fetal heart monitoring systems are not convenient for long-term continuous monitoring outside the confines of a hospital, owing to their cumbersome equipment, complex operation, and movement interference. Therefore, a flexible, wearable, and wireless fetal ECG monitoring system was developed in this work. Five flexible electrode patches were used to form multiple measurements and interference-elimination channels; the singular value decomposition algorithm was used to improve measurement accuracy. Based on the micromachining technology and laminated packaging technology, a multi-unit integrated electrode, transmission line, and processing circuit structure is designed and built, and flexible serpentine wire is used to provide ductility to the device. The resulting signal acquisition device is only 12.5 g in weight, and the electrode patch is 0.25 mm thick. The developed device can perfectly conform to skin, greatly improving the wearing comfort. The data can be wirelessly transmitted via Bluetooth, thereby enabling portable measurement anytime and anywhere. The clinical application demonstrated that the system could accurately detect fetal heart rate, maternal heart rate, and maternal uterine contractions. These results are in good agreement with a commercial Philips fetal monitor. The developed system can continuously monitor fetal heart rate for more than 6 h and thus provides a more effective long-term solution for fetal health monitoring. © 2022 Chinese Academy of Sciences. All rights reserved.
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页码：1912 / 1922
页数：10
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