Linking the chemical profile with the biological activities of Reaumuria alternifolia from Turkish flora

被引:0
|
作者
Terzic, Milena [1 ]
Dall'Acqua, Stefano [2 ]
Sut, Stefania [2 ]
Uba, Abdullahi Ibrahim [3 ]
Yildiztugay, Evren [4 ]
Koyuncu, Ismail [5 ]
Yuksekdag, Ozgur [5 ]
Zengin, Gokhan [6 ]
机构
[1] Univ Novi Sad, Fac Technol Novi Sad, Novi Sad, Serbia
[2] Univ Padua, Dept Pharmaceut & Pharmacol Sci, Via Marzolo 5, I-35121 Padua, Italy
[3] Istanbul AREL Univ, Dept Mol Biol & Genet, TR-34537 Istanbul, Turkiye
[4] Selcuk Univ, Fac Sci, Dept Biotechnol, TR-42130 Konya, Turkiye
[5] Harran Univ, Fac Med, Dept Med Biochem, TR-63290 Sanliurfa, Turkiye
[6] Selcuk Univ, Fac Sci, Dept Biol, TR-42130 Konya, Turkiye
关键词
Reaumuria alternifolia; Enzyme inhibitor activity; Cytotoxic activity; Phytoconstituents; Molecular docking; ANTIOXIDANT; ENZYME; TAMARICACEAE; PLANTS;
D O I
10.1016/j.molstruc.2024.140052
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The chemical composition and in vitro bioactivity of five Reaumuria alternifolia extracts obtained using solvents of different polarities (hexane, ethyl acetate, dichloromethane, methanol, and water) were investigated. LC-MSn analysis revealed the presence of phenolic acid derivatives, flavonoids, tannins, and anthocyanins as bioactive molecules in the examined plant material, the majority identified in the methanol extract. Bioactivity was evaluated in vitro through antioxidant, enzyme inhibitor, and cytotoxic assays. Extracts presented a significant biological potential, with the methanol extract being the most effective. The analyzed extracts showed that this readily available raw material is a rich source of phytonutrients, primarily antioxidant compounds. This research raises curiosity about the future perspective of Turkish Reaumuria alternifolia extracts, for the formulation of new products as nutritional supplements or improving the quality of existing products. These potential applications inspire hope for the future of natural product development and its impact on human health.
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页数:12
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