Optimization of Preparation Process and in Vitro Digestion Study of Anthocyanin/Fe3O4 Nanocomposites by Response Surface Methodology

被引：0
|
作者：
Niu Y. [1 ]
Wang Q. [1 ]
Han B. [1 ]
Peng X. [1 ]
机构：
[1] School of Public Healthy, Chengdu Medical College, Chengdu
来源：
Science and Technology of Food Industry | 2023年 / 44卷 / 13期
关键词：
anthocyanin/Fe[!sub]3[!/sub]O[!sub]4[!/sub] nanocomposites; antioxidant activity; in vitro digestion simulation; response surface methodology; structure characterization;
D O I：
10.13386/j.issn1002-0306.2022080100
中图分类号：
学科分类号：
摘要：
In order to improve the bioavailability of anthocyanins, a co-precipitation method was used to prepare anthocyanin/Fe3O4 nanocomposites in this study. The response surface method was used to optimize the synthesis of anthocyanin/Fe3O4 nanocomposites. The particle size analysis, Zeta potential measurement, scanning electron microscope, fourier transform infrared spectroscopy and in vitro digestion simulation of anthocyanin/Fe3O4 nanocomposites were carried out. The results showed that the optimum conditions for the preparation of anthocyanin/Fe3O4 nnanocomposites were anthocyanin/Fe3O4 mass ratio of 1:46, reaction time 19.6 h, reaction temperature 47 ℃. The encapsulation rate of anthocyanin under these conditions was 87.51%. The particle size distribution of anthocyanin/Fe3O4 nanocomposites was concentrated in the range of 100~1200 nm with uniform distribution, and the Zeta potential was −48.15 mV. The formation of spherical particles with smooth surfaces between anthocyanin and Fe3O4 nanoparticles was observed by scanning electron microscopy. The anthocyanin/Fe3O4 nanocomplexes showed anthocyanin C=O and C-H characteristic peaks at 1635 cm−1 and 1083 cm−1. The in vitro digestion simulation showed that the retention of anthocyanin was 91.99% and 46.23% in gastric and intestinal fluids. The scavenging ability of DPPH and ABTS+ radicals was increased in the intestinal fluid (P<0.05). Therefore, co-precipitation method can improve the bioavailability of anthocyanins, and provide technical support for the efficient utilization of anthocyanins. © 2023 Authors. All rights reserved.
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页码：167 / 175
页数：8
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