Process intensification of solution crystallization

被引：0
|
作者：
Feng Y. [1 ]
Chen K. [1 ]
Zhao J. [1 ]
Wang N. [1 ]
Wang T. [1 ]
Huang X. [1 ]
Zhou L. [1 ]
Hao H. [1 ,2 ]
机构：
[1] National Engineering Research Center of Industrial Crystallization Technology, School of Chemical Engineering and Technology, Tianjin University, Tianjin
[2] Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin
来源：
Huagong Jinzhan/Chemical Industry and Engineering Progress | 2024年 / 43卷 / 01期
关键词：
crystallization; growth; nucleation; particle size distribution; process intensification;
D O I：
10.16085/j.issn.1000-6613.2023-1146
中图分类号：
学科分类号：
摘要：
Solution crystallization is one of the most important product separation, purification and functionalization techniques in chemical industry, which is widely used in pharmaceutical, food, fine chemicals and other fields. The nucleation and growth process of crystals in solution crystallization will determine the key physicochemical properties such as crystal form, crystal habit, particle size and purity of the final crystal products. Therefore, process intensification of solution crystallization, especially crystal nucleation and growth process, can help to improve the process efficiency and meet the different performance requirements of crystal products. In this paper, process intensification strategies for nucleation and crystal growth in solution crystallization are systematically reviewed, including the technologies of confined space, physical fields, additives and template agents. The advantages and limitations of various process intensification strategies are discussed, and the main research focuses and development prospects of solution crystallization process intensification strategies are summarized. © 2024 Chemical Industry Press Co., Ltd.. All rights reserved.
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页码：87 / 99
页数：12
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