Research Progress of Sensors Technology Based on DNA Walker in Food Safety Detection

被引：0
|
作者：
Song S. [1 ]
Si X. [1 ]
Hu J. [1 ]
Du Z. [1 ]
Chen L. [1 ]
Liu J. [1 ]
机构：
[1] Beijing Sanyuan Foods Co., Ltd., National Engineering Research Center of Dairy Health for Maternal and Child, Beijing Engineering Research Center of Dairy, Technical Innovation Center of Human Milk Research, Beijing
来源：
Science and Technology of Food Industry | 2024年 / 45卷 / 12期
关键词：
biosensors; DNA walker; food safety; nucleic acid aptamers; signal amplification;
D O I：
10.13386/j.issn1002-0306.2023080091
中图分类号：
学科分类号：
摘要：
With the rapid development of DNA nanotechnology, DNA molecules with various structures and functions are used to construct programmable nanomachines with dynamic behaviors. Thereinto, DNA walker possesses the advantages of the cascade signal amplification generated by the autonomous movement along the predetermined track by driving force, which is widely applied in the biosensing, biological imaging, and drug delivery fields, thus showing the great application potential for rapid and ultrasensitive detection of contaminants in food. This review first briefly introduces the basic principles of DNA walker, and describes the strategies for improving the efficiency of DNA walker in detail, then summarizes its applications in the food safety detection. Finally, the future research directions of DNA walkers are prospected to provide theoretical guidance for its real applications. © The Author(s) 2024.
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页码：395 / 404
页数：9
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