Improvement of Mung Bean Seed-coat on Glucose/Lipid Metabolism in Diabetic Mice Induced by High-fat Diet Combined with Streptozotocin

被引：0
|
作者：
Hou D. [1 ,2 ]
Chen B. [2 ]
Wang H. [2 ]
Chen C. [2 ]
Shen Q. [2 ]
机构：
[1] School of Food and Health, Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing
[2] College of Food Science & Nutritional Engineering, Key Laboratory of Plant Protein and Cereal Processing, China Agricultural University, Beijing
来源：
Journal of Chinese Institute of Food Science and Technology | 2021年 / 21卷 / 07期
关键词：
Diabetic mice; Glucose and lipid metabolism; Improvement; Mung bean seed-coat;
D O I：
10.16429/j.1009-7848.2021.07.015
中图分类号：
学科分类号：
摘要：
The effects of mung bean seed-coat on glucose and lipid metabolism in diabetic mice by establishing a high-fat feeding combined with streptozotocin-induced diabetic mouse model was investigated. The results showed that, compared with the diabetic mice in the model group, a high-fat diet supplemented with mung bean seed-coat (6%) for 8 weeks could significantly reduced the blood glucose, blood lipid and glycated serum protein levels of mice in the intervention group (P<0.05). Moreover, the insulin secretion levels and glucose tolerance were significantly increased and improved by mung bean seed-coat supplementation(P<0.05), respectively. In addition, the hepatic and pancreatic histopathological observations showed that mung bean seed-coat supplementation could effectively relieve liver and pancreatic tissue damage and increase the number of islets β cells. The significant improvement effects of mung bean seed-coat on diabetic mice are of great practical significance for expanding its application and the development of auxiliary foods for reducing blood sugar. © 2021, Editorial Office of Journal of CIFST. All right reserved.
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页码：123 / 129
页数：6
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