In Vitro Digestion of Infant Formula Containing Partially Hydrolyzed Protein

被引:0
|
作者
Zhang S. [1 ]
Hu J. [1 ]
Peng X. [2 ]
Pan L. [2 ]
Dong L. [2 ]
Jiang Y. [2 ]
Wang J. [2 ]
Nie S. [1 ]
机构
[1] State Key Laboratory off Food Science and Technology, China-Canada Joint Lab off Food Science and Technology, Nanchang University, Nanchang
[2] Ausnutria Dairy (China) Co., Ltd, Ausnutria Institute off Food and Nutrition, Changsha
关键词
amino acid score; breast milk; in vitro protein digestion; infant formula; partial hydrolysis;
D O I
10.16429/j.1009-7848.2023.04.009
中图分类号
学科分类号
摘要
The dairy protein hydrolysis process can hydrolyze large molecule proteins into small molecule proteins and peptides. Infant formulas with partially hydrolyzed proteins may be beneficial to the digestion and absorption of infants, but the comparison between them and breast milk is unclear. In this study, a commercially available infant formula (EF) containing partially hydrolyzed protein was used to compare the in vitro digestion and absorption characteristics with standard infant formula (SF) and breast milk (BM), and the amino acid score and digestible indispensable amino acid score were calculated based on the total amino acid pattern and digested amino acid pattern, respectively, to evaluate the protein quality. The results showed that the protein content of the two formulas was higher than that of BM, and the amino acid composition was close to that of BM. The in vitro protein digestibility was (33.50±0.39)%, (33.07±0.83)% and (38.49±0.51)% for EF, SF and BM, respectively, with the absorption rate of EF up to 78% of the BM. The results of digestible indispensable amino acid score showed that the limiting amino acids of EF were threonine and histidine, while all other amino acids scored above 75, which can be considered as good protein quality. Therefore, the infant formula containing partially hydrolyzed protein used in this study has better digestibility and absorption properties than the control formula and is closer to breast milk. This study can provide data to support the digestion and absorption characteristics of infant formula containing partially hydrolyzed protein and provide a theoretical basis for in vitro research methods for protein evaluation. © 2023 Chinese Institute of Food Science and Technology. All rights reserved.
引用
收藏
页码:86 / 95
页数:9
相关论文
共 25 条
  • [1] GONG C Y, WANG ] Y, NIAN J, Et al., Research progress of amino acid composition in infant formulaVJW, China Dairy, 7, pp. 59-63, (2020)
  • [2] LIU S, CHEN Z Y., Effect of proteolysis products on infant growth VJW, Journal of Food Safety and ]uality Testing, 11, 2, pp. 363-367, (2020)
  • [3] CORRIGAN B, BRODKORB A., The effect of pretreatment of protein ingredients for infant formula on their in vitro gastro-intestinal behaviourVJW, International Dairy Journal, 110, (2020)
  • [4] I X Y, SU M Y, LIU C P, Et al., A review of whey hydrolysate formula in anti allergic research and market applicationsVJW, Food Industry, 36, 9, pp. 247-251, (2015)
  • [5] Dietary protein quality evaluation in human nutrition. Report of an FAO Eepert Consultation VMW, FAO Food and Nutrition Paper, 92, pp. 1-66, (2013)
  • [6] HAVENAAR R, MAATHUIS A, DE JONG A, Et al., Herring roe protein has a high digestible indispensable amino acid score (DIAAS) using a dynamic in vitro gastrointestinal modelVJW, Nutrition Research, 36, 8, pp. 798-807, (2016)
  • [7] DING ] A, NIE S P, HU J L, Et al., In vitro and in vivo gastrointestinal digestion and fermentation of the polysaccharide from Ganoderma atrum VJW, Food Hydrocolloids, 63, pp. 646-655, (2017)
  • [8] HU J L, NIE S P, MIN F F, Et al., Artificial simulated saliva, gastric and intestinal digestion of polysaccharide from the seeds of !lantago asiatica L. VJW, Carbohydrate Polymers, 92, 2, pp. 1143-1150, (2013)
  • [9] M$NARD O, BOURLIEU C, DE OLIVEIRA S C, Et al., A first step towards a consensus static in vitro model for simulating full -term infant digestion 3J5, Food Chemistry, 240, pp. 338-345, (2018)
  • [10] DUPONT D, MANDALARI G, MOLLE D, Et al., Comparative resistance of food proteins to adult and infant in vitro digestion models3J5, Molecular Nutrition & Food Research, 54, 6, pp. 767-780, (2010)