Cross-talk reduction in a multiplexed synchroscan streak camera with simultaneous calibration

被引：0

作者：

Hirmiz N. ^{[1
]}

Tsikouras A. ^{[2
]}

Osterlund E.J. ^{[3
]}

Richards M. ^{[2
]}

Andrews D.W. ^{[3
,4
,5
]}

Fang Q. ^{[1
,2
]}

机构：

[1] School of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, L8S 4L7, ON

[2] Department of Engineering Physics, McMaster University, 1280 Main Street West, Hamilton, L8S 4L7, ON

[3] Department of Biochemistry, University of Toronto, 27 King's College Cir, Toronto, M5S 1A8, ON

[4] Department of Biochemistry and Biomedical Sciences, McMaster University, Main Street West, Hamilton, L8S 4L7, ON

[5] Biological Sciences, Sunnybrook Research Institute, University of Toronto, 2075 Bayview Ave., Toronto, M4N 3M4, ON

来源：

Opt. Express | 2019年 / 16卷 / 22602-22614期

基金：

加拿大健康研究院; 加拿大自然科学与工程研究理事会;

关键词：

Crosstalk;

D O I：

10.1364/OE.27.022602

中图分类号：

学科分类号：

摘要：

The streak camera is a picosecond resolution photodetector with parallel input capability; however, the degree of multiplexing is limited by crosstalk and temporal uncertainty in the sweeping field. We introduced a fixed time delay between adjacent fibers to reduce crosstalk in the synchroscan mode. The fixed delay and a tunable electronic delay between the input pulse and the synchroscan unit allows robust separation modes between the streaks, while spatial and temporal nonlinearities can be calibrated in. The efficacy of the design is demonstrated through a 100-fold multiplexed confocal fluorescence lifetime imaging microscope in live cells. © 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

引用

页码：22602 / 22614

页数：12

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