Application of microspheres in calcium phosphate cement system

被引：0

作者：

Lin S. ^{[1
]}

Qu S. ^{[2
]}

Xue J. ^{[1
]}

Lin C. ^{[1
]}

Xu X. ^{[1
]}

Weng J. ^{[2
]}

机构：

[1] Clinical Engineering Department, The Second Affiliated Hospital, Yuying Children's Hospital of Wenzhou Medical College, Wenzhou

[2] Key Lab of Advanced Technologies of Materials, School of Material Science and Engineering, Southwest Jiaotong University, Chengdu

来源：

Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering | 2016年 / 33卷 / 04期

关键词：

Calcium phosphate cement (CPC); Drug release; Microspheres; Porous structure;

D O I：

10.7507/1001-5515.20160130

中图分类号：

学科分类号：

摘要：

Calcium phosphate cement (CPC) has been widely used as bone fillers because of its excellent bioactivity and biocompatibility. Meanwhile, CPC is also an attractive candidate for the incorporation of drug or microspheres, because the preparing procedure avoids sintering and heating release. This paper summarizes the clinical applications of microspheres incorporated in CPC from the aspects of sustained drug release, accelerated degradation, porous structure and improved mechanical properties. The paper is aimed to analyze the methods and principles of microspheres loaded CPC, and so as to lay a foundation for the further research of improving and manufacturing the CPC with ideal properties. © 2016, Editorial Office of Journal of Biomedical Engineering. All right reserved.

引用

页码：806 / 811

页数：5

共 37 条

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