Effect of PLA knitted structure on the mechanical properties of composite vascular scaffold

A new entire biodegradable scaffold has been developed which does not require precellularization before transplantation. This new kind of vascular scaffold prototype made from porous poly-Ε-caprolactone (PCL) membrane to provide three-dimensional environment for cell growth, and embedded with weft-knitted polylactic acid (PLA) fabric to support mechanics. The aim of this paper is to study the variation tendency of mechanical properties with the fabric spacing changing. The basic geometrical parameters were measured to characterize properties of the samples. The tensile and compressive elastic recovery of the samples were tested by the universal mechanical tester and radial compression apparatus, respectively. Both tensile and compressive properties enhanced when reducing the fabric spacing of the composite vascular scaffold. Copyright © 2014 Editorial Department of Journal of Donghua University. All rights reserved.