Research Progress on Structure and Function of CRISPR-Cas Systems in Foodborne Pathogens

被引：0
|
作者：
Wang X. [1 ]
Zhuo Q. [1 ]
Wu Y. [2 ,3 ]
Liu Y. [1 ]
Li H. [1 ]
Dong Q. [1 ]
机构：
[1] School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai
[2] Technology Center of Zhangjiagang Customs, Suzhou
[3] Centre of Analysis and Test, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai
来源：
Journal of Chinese Institute of Food Science and Technology | 2021年 / 21卷 / 11期
关键词：
Biofilm; CRISPR; Drug resistance; Foodborne pathogens; Virulence;
D O I：
10.16429/j.1009-7848.2021.11.036
中图分类号：
学科分类号：
摘要：
Clustered regularly interspaced short palindromic repeats(CRISPR) system and CRISPR-associated proteins (Cas) make up CRISPR-Cas system which is one part of the immune system exists in bacteria and archaea, and can defend against the invasion of foreign mobile genetic elements such as phages effectively. Studies have found this system can prevent foreign nucleic acids which carrying feature genes integrating into bacterial genome and has effect on regulating functional genes expression, it is essential for biological characteristics such as bacterial virulence, antibiotics resistance, and the ability of biofilm formation. This article analyzed the structure of CRISPR-Cas in the common foodborne pathogens, and reviewed the functional correlation between CRISPR-Cas system and bacterial virulence, antibiotics, biofilm formation and typing, provided a reference for subsequent functional research of CRISPR-Cas system and traceability and control of foodborne pathogens. © 2021, Editorial Office of Journal of CIFST. All right reserved.
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页码：329 / 336
页数：7
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