A Skin Model Simulating Humidity Response Features and Mechanical Properties of Human Skin

被引：0
|
作者：
Chen J. [1 ,2 ]
Li J. [2 ]
Chen J. [1 ,2 ]
Zeng X. [2 ]
机构：
[1] School of Environmental and Chemical Engineering, Shanghai University, Shanghai
[2] Laboratory for Advanced Lubricating Materials, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai
来源：
Cailiao Daobao/Materials Reports | 2019年 / 33卷 / 11期
基金：
上海市自然科学基金;
关键词：
Artificial skin model; Elastic modulus; Hydration; Water swelling rate;
D O I：
10.11896/cldb.18090279
中图分类号：
学科分类号：
摘要：
High-quality artificial skin model (ASM) plays a critical role in developing skin contacted materials, accordingly, the great efforts have been paid in the research of ASM. In this study, an artificial skin model was constructed by chitosan (CTS) hydrogel and polydimethylsiloxane (PDMS), aiming at simulating the humidity response and mechanical properties of human skin. Furthermore, the impact of the mass ratio of CTS and PDMS, and the content of curing agent on the performance of ASM were investigated. It was found that the increase of curing agent content contributed to the raise of hydration level and swelling rate of the ASM. The prepared ASM would well simulated diverse hydration degrees of human skin with mass ratio of the curing agent to the polydimethylsiloxane of less than 1:20. The results of UST test indicated that the reduction of curing agent content would lead to the decline of elastic modulus of ASM. When the mass ratio of curing agent and PDMS was reduced to 1:50, the ASM exhibited similar variation behaviors of elastic modulus to depth with human skin in inner forearm. Additionally, the elastic modulus of dry ASM was higher than that of wet ASM, which was consistent with the characteristics of human skin. © 2019, Materials Review Magazine. All right reserved.
引用
收藏
页码：3829 / 3832
页数：3
相关论文
共 15 条
  • [1] Zeng X., Van der Heide E., Skin Care Supplement to Household and Personal Care Today, 10, 2, (2015)
  • [2] Derler S., Gerhardt L.C., Tribology Letters, 45, 1, (2012)
  • [3] Van der Heide E., Zeng X., Friction, 1, 2, (2013)
  • [4] Tan M., Li L.S., Chemistry Bulletin, 63, 11, (2000)
  • [5] Lin L., Li J., Zeng X., Journal of the Society of Biomechanisms, 41, 3, (2017)
  • [6] Van Der Heide E., Lossie C.M., Van Bommel K.J.C., Et al., Tribology Transactions, 53, 6, (2010)
  • [7] Guerra C., Tribology Letters, 44, 2, (2011)
  • [8] Morales-Hurtado M., Zeng X., Gonzalez-Rodriguez P., Et al., Journal of the Mechanical Behavior of Biomedical Materials, 46, (2015)
  • [9] Lin L., Li J., Zeng X., Journal of the Society of Biomechanisms, 41, 3, (2017)
  • [10] Nachman M., Franklin S.E., Tribology International, 97, (2016)
12