Recent Progress in the Preparation and Application of Absorption-enhanced Colon-targeted Delivery System

被引：0
|
作者：
Wang H. [1 ]
Chen M. [1 ]
Xiao J. [1 ,2 ]
机构：
[1] College of Food Science, South China Agricultural University, Guangzhou
[2] Guangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, Guangzhou
来源：
Shipin Kexue/Food Science | 2022年 / 43卷 / 03期
关键词：
Absorption-enhanced; Colon-targeted; Delivery system; Evaluation methods; Preparation methods;
D O I：
10.7506/spkx1002-6630-20200820-276
中图分类号：
学科分类号：
摘要：
The absorption-enhanced colon-targeted delivery system is a novel colon-targeted delivery system with outstanding colonic adhesion capacity and enhanced colonic absorption function.Compared with the traditional colontargeted delivery system, it has some advantages such as precisely control of release sites and action time, increased specific surface area and enhanced targeted adhesion efficiency.In this paper, we review the literature on absorption-enhanced colon-targeted delivery systems in terms of their types, structures and preparation methods as well as substances that can be delivered using them, and we summarizes the in vivo and in vitro evaluation methods for absorption-enhanced colontargeted delivery systems.Moreover, we give an outlook on the current and potential applications of absorption-enhanced colon-targeted delivery systems.Through this review, we conclude that absorption-enhanced colon-targeted delivery systems provide a feasible and innovative method to analyze the mechanism behinds the health benefits of foodborne biocompounds. © 2022, China Food Publishing Company. All right reserved.
引用
收藏
页码：352 / 361
页数：9
相关论文
共 88 条
  • [1] GREENWOOD-VAN MEERVELD B, JOHNSON A C, GRUNDY D., Gastrointestinal physiology and function, Gastrointestinal pharmacology, pp. 1-16, (2017)
  • [2] XIAO J, CAO Y, HUANG Q., Edible nanoencapsulation vehicles for oral delivery of phytochemicals: a perspective paper, Journal of Agricultural and Food Chemistry, 65, 32, pp. 6727-6735, (2017)
  • [3] DURAN-LOBATO M, NIU Z, ALONSO M J., Oral delivery of biologics for precision medicine, Advanced Materials, 32, 13, (2020)
  • [4] TRIPATHI J, THAPA P, MAHARJAN R, Et al., Current state and future perspectives on gastroretentive drug delivery systems, Pharmaceutics, 11, 4, (2019)
  • [5] ZHANG F, HE F, LI L, Et al., Bioavailability based on the gut microbiota: a new perspective, Microbiology and Molecular Biology Reviews, 84, 2, pp. e00072-19, (2020)
  • [6] PAONE P, CANI P D., Mucus barrier, mucins and gut microbiota: the expected slimy partners?, Gut, 69, 12, pp. 2232-2243, (2020)
  • [7] ENCK K, BANKS S, YADAV H, Et al., Development of a novel oral delivery vehicle for probiotics, Current Pharmaceutical Design, 26, 26, pp. 3134-3140, (2020)
  • [8] DEVASSY J G, NWACHUKWU I D, JONES P J H., Curcumin and cancer: barriers to obtaining a health claim, Nutrition Reviews, 73, 3, pp. 155-165, (2015)
  • [9] RAUF A, IMRAN M, BUTT M S, Et al., Resveratrol as an anti-cancer agent: a review, Critical Reviews in Food Science and Nutrition, 58, 9, pp. 1428-1447, (2018)
  • [10] LEE S H, BAJRACHARYA R, MIN J Y, Et al., Strategic approaches for colon targeted drug delivery: an overview of recent advancements, Pharmaceutics, 12, 1, (2020)
123456789