Advances in numerical simulation of blast-induced traumatic brain injury: modeling, mechanical mechanism and protection

被引：0
|
作者：
Kang Y. [1 ]
Ma T. [1 ]
Huang X. [1 ]
Zhuang Z. [2 ]
Liu Z. [2 ]
Zeng F. [3 ,4 ]
Huang C. [3 ,4 ]
机构：
[1] Systems Engineering Institute, Academy of Military Science, Beijing
[2] School of Aerospace Engineering, Tsinghua University, Beijing
[3] CAEP Software Center for High Performance Numerical Simulation, Beijing
[4] Institute of Applied Physics and Computational Mathematics, Beijing
来源：
Baozha Yu Chongji/Explosion and Shock Waves | 2023年 / 43卷 / 06期
关键词：
blast wave; injury mechanism; modeling; protection; traumatic brain injury;
D O I：
10.11883/bzycj-2022-0521
中图分类号：
学科分类号：
摘要：
Blast-induced traumatic brain injury (bTBI) is a prevalent consequence of modern warfare and explosion hazards. In recent years, mild primary brain injury caused by blast waves has become the predominant form of injury, garnering significant attention from researchers. Due to ethical and technical limitations, human testing is challenging to conduct; therefore, numerical simulation has emerged as one of the most critical methods for studying bTBI. By combining reasonable physical modeling with reliable modes, we can quantitatively predict the biomechanical response of the human head and brain to blast waves. This approach reveals the mechanical mechanisms underlying brain injury, which is essential for understanding bTBI's biomechanical characteristics and designing protective equipment for individuals. The aim of this review is to furnish a comprehensive overview of the current research on numerical simulation of primary bTBI, encompassing advancements in computational modeling, mechanical mechanisms and protective measures. Focusing on the multi-scale nature of the human brain and biomechanical modeling of bTBI, this article introduces linear elastic, hyper-elastic, and viscoelastic constitutive models for brain tissue; development and evolution of finite element models for the human head in terms of brain structure and mesh size; as well as macroscopic, mesoscopic, and multi-scale modeling methods along with numerical simulation techniques for bTBI. Aiming at the direct effects of wave propagation, cerebral vasculature influence, and the continuous process of bodily response, the mechanical mechanism obtained through numerical simulation is analyzed and discussed. The advancements in numerical simulation of protective strategies for bTBI, including the significance of enhancing head closure and the implementation of novel structures and materials, are expounded upon. Ultimately, a summary is provided regarding current research and application of numerical simulation for bTBI, along with an assessment of future development and improvement. © 2023 Explosion and Shock Waves. All rights reserved.
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