Taking Xilin River Basin and Balager River Basin of Inner Mongolia as typical plateau inland river basins, we analyzed the hydrometeorology mutation characteristics (e. g. air temperature, precipitation and runoff), ecological evolution pattern (e. g. normalized difference vegetation index (NDVI)), and their relationship in the past 55years. Based on methods of mathematical statistics, Mann-Kendall test, climate tendency, Kriging spatial interpolation and remote sensing interpretation, the results showed compared with Balager River Basin, Xilin River Basin has a higher degree of drought, higher air temperature, smaller precipitation and runoff depth, less precipitation days and runoff days, lower runoff coefficient. In Xilin River Basin, the air temperature showed a more dramatic increasing tendency and earlier mutation year. The warming rates in both regions were beyond 0.2℃/10a. At annual scale, there were substantial difference in the mutation time and the sequence, driving factors and change values of before and after mutation time for the runoff coefficient, precipitation, and runoff between these two regions. The spatial distributions of seasonal precipitation were different between the two places exist different. The maximum NDVI of the two places were similar to the spatial distribution characteristics of winter precipitation, i. e., concentrating in the upper river valleys. © 2019, Editorial Board of China Environmental Science. All right reserved.