Evaluation of the Effectiveness of Combined Treatment with Intravaginal Diazepam and Pelvic Floor Rehabilitation in Patients with Vulvodynia by Ultrasound Monitoring of Biometric Parameters of Pelvic Muscles: A Pilot Study

被引:0
|
作者
Merlino, Lucia [1 ]
Ciminello, Enrico [2 ]
Volpicelli, Agnese Immacolata [3 ]
Tillier, Stefano [3 ]
Pasquali, Marianna Francesca [4 ,5 ]
Dominoni, Mattia [4 ,5 ]
Gardella, Barbara [4 ,5 ]
Senatori, Roberto [6 ]
Dionisi, Barbara [6 ]
Piccioni, Maria Grazia [1 ]
机构
[1] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, I-00161 Rome, Italy
[2] Italian Natl Inst Hlth, I-00161 Rome, Italy
[3] Univ Piemonte Orientale, Sch Gynecol & Obstet, I-28100 Novara, Italy
[4] Univ Pavia, Dept Clin Surg Diagnost & Pediat Sci, I-27100 Pavia, Italy
[5] IRCCS Fdn Policlin San Matteo, Dept Obstet & Gynecol, I-27100 Pavia, Italy
[6] Vulvar Pathol Study Ctr, I-00161 Rome, Italy
关键词
vulvodynia; pelvis floor; rehabilitation; pain; PROVOKED VESTIBULODYNIA; PHYSICAL-THERAPY; VAGINAL DIAZEPAM; WOMEN; OUTCOMES; PAIN;
D O I
10.3390/diseases12080174
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
(1) Background: Vulvodynia is characterized by vulvar pain for at least three months and may have related variables, one of these being pelvic floor hypertonus. The purpose of this study was to compare the therapeutic effectiveness of two weekly sessions of pelvic floor rehabilitation and 5 mg of vaginal diazepam daily vs. pelvic floor rehabilitation alone in individuals with vulvodynia. (2) Methods: A single-center, not-blind, randomized study enrolled 20 vulvodynic patients: A total of 10 were treated with dual therapy (intravaginal diazepam and pelvic floor rehabilitation), and 10 were treated with only pelvic floor rehabilitation. All of them underwent a pelvic floor ultrasound examination and VAS pain and Marinoff scale assessments before the beginning of therapy as well as three and six months later. (3) Results: The elevator plate angle ranged from 8.2 to 9.55 (p = 0.0005), hiatal area diameter ranged from 1.277 to 1.482 (p = 0.0002), levator symphysis distance ranged from 3.88 to 4.098 (p = 0.006), anorectal angle ranged from 121.9 to 125.49 (p = 0.006), Marinoff scale ranged from 2.3 to 1.4 (p = 0.009), and VAS scale ranged from 5.8 to 2.8 (p < 0.001). (4) Conclusions: This pilot study demonstrates that the suggested treatment improves the hypertonicity of the pelvic floor, as measured by ultrasound parameters, correlating with a reduction in symptomatology.
引用
收藏
页数:10
相关论文
共 16 条
  • [1] Botulinum toxin A (Botox) injection into muscles of pelvic floor as a treatment for persistent pelvic pain secondary to pelvic floor muscular spasm: A pilot study
    Mooney, Samantha S.
    Readman, Emma
    Hiscock, Richard J.
    Francis, Alaina
    Fraser, Elise
    Ellett, Lenore
    AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, 2021, 61 (05): : 777 - 784
  • [2] The Evaluation of Bioelectrical Activity of Pelvic Floor Muscles Depending on Probe Location: A Pilot Study
    Halski, Tomasz
    Ptaszkowski, Kuba
    Slupska, Lucyna
    Dymarek, Robert
    BIOMED RESEARCH INTERNATIONAL, 2013, 2013
  • [3] Diagnosis of functional defecation disorders by ultrasound evaluation of pelvic floor dynamic in constipated patients: A pilot study
    Lambiase, C.
    Ricchiuti, A.
    Rettura, F.
    Grosso, A.
    Bottari, A.
    Sciume, G. D.
    Berti, G.
    De Bortoli, N.
    Bellini, M.
    NEUROGASTROENTEROLOGY AND MOTILITY, 2023, 35
  • [4] Novel insight into the coordination between pelvic floor muscles and the glottis through ultrasound imaging: a pilot study
    Rudavsky, Aliza
    Turner, Tricia
    INTERNATIONAL UROGYNECOLOGY JOURNAL, 2020, 31 (12) : 2645 - 2652
  • [5] Novel insight into the coordination between pelvic floor muscles and the glottis through ultrasound imaging: a pilot study
    Aliza Rudavsky
    Tricia Turner
    International Urogynecology Journal, 2020, 31 : 2645 - 2652
  • [6] Effectiveness of a Pelvic Floor Muscle Training Based on Intravaginal Electrical Stimulation for the Treatment of Urinary Incontinence in Women With Multiple Sclerosis: A Pilot Study.
    Magni, Eleonora
    Dominguez, Anabel Granja
    Hochsprung, Anja
    MULTIPLE SCLEROSIS JOURNAL, 2017, 23 (06) : 894 - 894
  • [7] The impact of short-term pelvic floor muscle training on the biomechanical parameters of the pelvic floor among patients with stress urinary incontinence: A pilot study
    Ratonyi, David
    Koroknai, Erzsebet
    Pakozdy, Krisztina
    Sipos, Attila G.
    Takacs, Peter
    Krasznai, Zoard Tibor
    Kozma, Bence
    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2024, 302 : 283 - 287
  • [8] EVALUATION OF THE EFFECT OF PELVIC FLOOR ULTRASOUND ON PRELIMINARY SCREENING AND REHABILITATION TREATMENT OF PRIMIPARA POSTPARTUM STRESS URINARY INCONTINENCE
    Chen, Xiaoran
    Zhang, Zhongsheng
    Jiang, Meiping
    Yuan, Zhongkai
    Zhang, Jiwen
    ACTA MEDICA MEDITERRANEA, 2020, 36 (02): : 1175 - 1179
  • [9] Pelvic Floor Biometric Changes Assessed by 4D Translabial Ultrassound in Women With Vulvodynia Submitted to Physical Therapy: A Pilot Study of a Randomized Controlled Trial
    Bardin, Marcela Grigol
    Giraldo, Paulo Cesar
    Martinho, Natalia
    JOURNAL OF SEXUAL MEDICINE, 2020, 17 (11): : 2236 - 2246